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Alcohol Use: Global Public Health Impact. Camila M. Silveira, MD, PhD University of São Paulo. Global Alcohol Use. 2 billion worldwide drink ~1.4 billion moderate → health benefits ~600 million harmful use → global public health problem 76 million → alcohol use disorders (AUD)
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Alcohol Use: Global Public Health Impact Camila M. Silveira, MD, PhD University of São Paulo
Global Alcohol Use • 2 billion worldwide drink • ~1.4 billion moderate → health benefits • ~600 million harmful use → global public health problem • 76 million → alcohol use disorders (AUD) • 60+ diseases and injuries • Relationship alcohol ↔ health is complex
Dimensions of Alcohol Use The Society Demography Acceptable Patterns Availability Age Gender Income How Much The Pattern The Beverage Problems The Person
This Lecture Will Cover • Measures and health impact • Geographical and cultural differences • Gender and demographic differences • Health care implications • Prevention of harmful use
Different Measures • Per capita consumption (PCC) • Drinking patterns • Comparative risk assessment (CRA) • Alcohol use disorders • Global burden
Per Capita Consumption • (production + imports) – exports population • Useful: • Monitor consumption • Limitations: • Unrecorded consumption • Abstainers • Drinking patterns
Different Measures • Per capita consumption • Drinking patterns • Comparative risk assessment (CRA) • Alcohol use disorders • Global burden
Standard Drink • ~10 gm pure alcohol • 12 oz. beer • 5 oz. wine • 1 oz. spirits
DrinkingPatterns • ModerateDrinking: • up to 2 drinks/day ♂ • up to 1 drink/day ♀
ModerateDrinking • Benefits • Heart attacks • Stroke • Cognitive impairment • Gall stones • Diabetes mellitus • Problems ~7% • Sleep disruption • Liver diseases
People Who Should Not Drink • Children and adolescents • Pregnant • Drivers • Medications • Certain medical conditions
DrinkingPatterns • HighRiskDrinking: • Men: > 14 drinks/weekOR > 4 drinks/day • Women: > 7 drinks/week OR > 3 drinks/day
HighRiskDrinking (cont’d) • Danger ↑ as intake ↑: • 3x laryngeal cancer • 3x blood pressure • 4x fatty liver • Infections
Drinking Patterns • Heavy Episodic Drinking (HED): • 5+ drinks/occasion ♂ • 4+ drinks/occasion ♀ • BAC > 0.08 gm%
Risks of HED • Vehicle crashes • Violence • Unsafe sex • Unintended pregnancy • Heart diseases • Psychosocial problems • Psychiatric symptoms
Different Measures • Per capita consumption • Drinking patterns • Comparative risk assessment (CRA) • Alcohol use disorders • Global burden
Comparative Risk Assessment (CRA) • Heavy drinking occasions • High usual quantity/occasion • Frequency festive drinking • Proportion drinking occasions/getting drunk • Drinking daily or nearly daily • Drinking in public places • Drinking with meals
Different Measures • Per capita consumption • Drinking patterns • Comparative risk assessment (CRA) • Alcohol use disorders • Global burden
Alcohol Use Disorders Dependence 3+ in same 12 mos: • Tolerance • Withdrawal • ↑ amts. or more time • Desire/inability to ↓ • ↓ other activities • ↑ obtain, use, recover • ↑ consequences Abuse 1+ in same 12 mos: • ↓ role obligations • Hazardous use • Legal problems • Interpersonal problems • dependence
Different Measures • Per capita consumption • Drinking patterns • Comparative risk assessment (CRA) • Alcohol use disorders • Global burden
Global Burden of Disease • Deaths • DALY: Disability-Adjusted Life Years: • Life yrs lost from early death • Healthy years lost from: • Poor health • Disability
DeathsWorldwide 2.5 million deaths/yr (4% of total)
Burden of Disease Worldwide 3rdleading cause of DALYs
This Lecture Will Cover • Measures and health impact✔ • Geographical/cultural differences • Gender and demographic differences • Health care implications • Prevention of harmful use
Per Capita Consumption (PCC) PCC in litres pure alcohol 0 – 6 L 6 – 12 L 12 – 25 L
Prevalence of Abstention % Abstention 0% - 40% 40%-60% 60%-100%
DrinkingPatterns (CRA) Drinking Patterns 1 - 2 2 – 2.5 2.5 – 3.5 3.5 - 4
Summary E Europe worst all measures Developing countries near top on CRA (middle PCC, abstinence) E Med and Africa near top on CRA (↓PCC↑ abst) W Europe lowest CRA (↑ PCC ↓ abst)
This Lecture Will Cover • Measures and health impact✔ • Geographical/cultural differences✔ • Gender and demographic differences • Health care implications • Prevention of harmful use
Women Have: • ↑BAC/drink ▪↓ muscle → ↓ body water ▪↓ first pass metabolism • ↑ hormone/reproduction problems ▪ ↓ progesterone ▪ ↑ estradiol ▪ ↓ luteinizing hormone • ↑ some health risks ▪ Breast cancer ▪ Harm to fetus • Remember women also: ▪ ↑ abstain ▪Genders are converging ▪ ↓ HED
HED Demography • Age • 18–24 most common HED • Earlier onset HED ↑risk of AUD • Ethnicity (USA) • White non Hispanics: ↓ drinks per HED episode • Other than white: ↑ drinks per HED episode • Marital status • single > married
HED Beverage Type • USA adolescents and young adults • Beer>spirits>wine • Alcohol-pops ↑ concern (adolescents) • European adults • ↑ HED beer/spirits (E Europe) • ↓ HED if wine with meals (W Europe)
HED College • College 12 mo prevalence • USA/ Brazil: ~40% (Male/Female ratio~ 1:1) • Alc problems USA • 100,000 victims of sexual assault • 600,000 injuries • 700,000 assaults • 3.4 million drove under influence • 25% negative academic consequences
This lecture will cover • Measures and health impact✔ • Geographical/cultural differences✔ • Gender and demographic differences✔ • Health care implications • Prevention of harmful use
Health Care Implications • ~ 45% with HED see MD • MD needs to ask: • Quantity/frequency/pattern use • Alcohol problems • Consider gender and cultural differences • Consider use of CAGE
CAGE C: Felt you should cut down your drinking A:Annoyed you by criticizing your drinking G: Felt guilty about your drinking E: Drink in AM to ↓ symptoms (eye-opener)
Health Care Implications Abstinent: don’t encourage to start Moderate drinkers: explain risks Hazardous drinkers: brief intervention Abuse/dependence: refer to specialist
Brief Intervention • Target: primary care physicians • Effective: non alcohol dependent subjects • Goal: moderate drinking not abstinence • 4 sessions or fewer (just a few minutes). • Elements of Brief Intervention- FACT • Feedback • Advice • Commitment • Tracking
This Lecture Will Cover • How to measure use and problems✔ • Geographical/cultural differences✔ • Gender and demographic differences✔ • Health care implications ✔ • Prevention of harmful use
Targets To ↓ HED • Leadership, awareness and commitment • Health services • Community action • Drink–driving policies • Availability of alcohol • Marketing of alcoholic beverages • Pricing policies • ↓ negative alcohol consequences • ↓ public health impact of illicit alcohol
Special Steps for Colleges Campus-based Education efforts Treat students who have HED Parent-based intervention
This Lecture Covered • How to measure use and problems✔ • Geographical/cultural differences✔ • Gender and demographic differences✔ • Health care implications ✔ • Prevention of harmful use ✔
KeyMessages • Different measures of alc use/problems • Countries differ on problem rates • Global problems need global interventions • Act globally • Interventions: effective but underused • Health systems: transform to meet new challenges