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Predictive Impact of Transforming Growth Factor-Beta Gene Expression in Mouse Hepatocytes on Cancer Outcomes

This study investigates the role of transforming growth factor-beta (TGF-β) gene expression signatures in mouse hepatocytes and their potential as predictive markers for clinical outcomes in human cancer. The findings suggest that specific gene expression profiles can inform prognosis and treatment strategies, highlighting the relevance of TGF-β pathways in cancer biology. The research emphasizes the importance of using animal models in understanding the mechanisms of disease and improving personalized medicine approaches.

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Predictive Impact of Transforming Growth Factor-Beta Gene Expression in Mouse Hepatocytes on Cancer Outcomes

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  1. * 9. Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer. Hepatology 2008;47:2059-2067.

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