Department of Medicine Task Force on Research

1. Department of Medicine Task Force on Research

2. Committee Charge • Develop a unifying vision to become leaders in translational research • Achieve top 10 status nationally • Develop common strategies for success across Divisions • Training of future physician-scientists • Recruiting and supporting translational scientists • Building the infrastructure for the full range of translational research (i.e., T1 - T4) • Increasing the number of “large” R, P, U grants (clinical, multi-investigator, etc.)

3. Where are we now ? (24) (20)

4. Strengths • Regional (and in some cases national) recognition in a broad array of clinical specialties and research areas. • Auto-immunity & inflammation; the microbiome, cardiovascular disease, asthma; single-site and growing strength in multi-site clinical trials and trial coordinating. • A cadre of successful physician-investigators with robust research programs in the Department of Medicine. • Access to unique patient populations (TH, BV, VA) and healthcare systems for clinical and population-based research. • Strong philanthropic base

5. Weaknesses • Lack of integrated Departmental research vision & strategy • Lack of alignment of an Institutional research mission with our clinical and educational missions • Under-developed Departmental research infrastructure • Limited exposure of trainees to successful physician-investigators • Poor record of recruiting/retaining our own top trainees • Ad hoc nature of recruitment process • Identification of candidates, startup packages, benchmarks of success

6. Threats • Very unfavorable funding environment at NIH and other governmental agencies • Changing healthcare systems may impact clinical revenue stream • Actual and perceived damage to NYU Langone Medical Center by Hurricane Sandy • Competition from other academic medical centers both locally and nationally for top talent • New research buildings at Sinai, Cornell, MSK, & Columbia

7. Opportunities • Restructure our training programs to enhance the development of academic physician-investigators. • Build translational programs around strategically important patient populations that can enhance our reputation • Common diseases (CV, DM, etc.) as well as niche/rare diseases. • Align Departmental recruitment with Institutional strategic priority areas • Genomics, metabolomics, inflammation, stem cells & regenerative medicine, experimental therapeutics, imaging (potential examples) • Restructure our teaching hospitals and our outpatient practice sites • Enhance patient-based clinical and translational research. • Expand our philanthropic base to offset declines in NIH funding.

8. Department of MedicineDisease-Centered Strategy Metabolic Diseases (DM, Obesity) Cardiovascular Diseases (CAD, CHF, SCD, AF) Auto Immunity, Infection and Inflammation (SLE, RA, IBD) Aging and Alzheimers (Dementia) Basic and T1 – T4 Translational Research Programs Basic Scientists Translational Investigators Population/Database Stem Cells & Regenerative Med Metabolomics Imaging Medical Genomics Experimental Therapeutics Institutional Cross-Disciplinary Strategic Focus Areas and Cores (possible areas)

9. NIH Rankings: 2020