Objective:Development of consumer perceived efficacious hair fall reduction product

1. Objective:Development of consumer perceived efficacious hair fall reduction product • Types of Hair : There are three types of Hair in Human beings • Lenugo : The first hair to be produced by fetal follicles,is fine,soft,unmedullated and usually unpigmented, this is generally shed in the Utero in the seventh or eighth month of gestation. • Vellus Hair: Vellus hair is soft unmedullated,usually unpigmentedand seldom more than 2cm long. • Terminal Hair :Terminal hair is large and coarse with medulla & pigmented and can vary in length.At birth it is found as scalp hair,eye brow,eye lashes. • Chemical Composition of Hair : • Protein : The main component of hair is protein ,which is 65-9% by weight.The protein is Keratinous and is condensation polymer of Amino acids. • Water , Lipids and Trace elements are other constituents.

2. Objective:Development of consumer perceived efficacious hair fall reduction product

3. Objective:Development of Consumer perceived efficacious hair fall reduction product Hair - Cycle

4. Objective :Development of consumer perceived efficacious hair fall reduction product Average Distribution of Anagen, Catagen and Talogen Hairs

5. Objective : Development of consumer perceived efficacious hair fall reduction productReasons for Hair Fall – The 7- H Concept Hormones Hair dressing Heredity Healing Health Hassles Hunger

6. Objective:Development of consumer perceived efficacious hair fall reduction product Clinical Reasons For Hall Fall & Its Treatment I) Androgenic Alopecia (Male and Female Pattern Baldness) • Responsible for 85- 90% of hair fall • Male sex hormone, testosterone (which is also present in females in a small amount) is converted in a substance known as Dihydro-Testosterone (DHT) in certain cells, by an enzyme 5- reductase. • This DHT is responsible in reduction of Hair Follicle diameter and their eventual shrinkage. • This action of DHT is determined by the genetic predisposition in the individual’s Hair Follicles • Treatment involves Finasteride (5- reductase. Inhibitor) Minoxidil ( a vasodilator), and some surgical techniques like Hair Transplant.

7. Objective :Development of Consumer Perceived efficacious Hair Fall Reduction ProductEffect Of DHT - Miniaturisation Of Hair Follicles • Transformation of terminal follicles to vellus type follicles • Premature completion of Anagen phase, which in turn yields follicles which are thinner and shorter than the normal terminal hair follicles. The follicles go in their resting phase faster due to shortening of their growing phase. • Over a period of time, the Hair follicles gradually shut down and become dormant i.e hair grows shorter and shorter with each cycle and finally terminal hair becomes vellus type of hair

8. Objective : Hair Fall -TreatmentObjective : Development ofconsumer perceived efficacious hair fall reduction product From this To this Most common type of Hair Loss in Men From this To this Most common type of Hair Loss in women

9. Objective :Development of consumer perceived efficacious hair fall reduction productClinical Reasons For Hair Fall And Its Treatment contd. II) Anagen Effluvium • Sudden loss of hair as a result of chemicals or irradiation such as the hair loss that results from certain types of chemotherapy and radiation treatment • Hair loss is usually sudden occurring 1-3 weeks after exposure to the chemical or radiation • This hair loss is mostly temporary

10. Way -Forward • Efficacious product for Male Pattern Baldness : • There is need toget an effective product for Male Pattern Bald ness(MPB),this is also applicable to Female ,bur not as severally as in men. • Some Allopathic drugs (Minoxidil, Propecia etc.) are available and are US FDA approved,they have side effects and have limitations . • There is need to develop Natural /Herbal /Ayurvedic product with proven efficacy . • There is growing trend of hair loss and Bald ness .

11. Light Hair oil • Concept of Light Hair Oil • Habit of oiling is reducing globally. • It is very important to deliver the goodness of oil in Non –oily format. • There is proven benefit of massaging with oil on the scalp. • It is necessary to understand the concept of “Oily Feel”,we Know some oils have oily feel where as some do not have as oily feel. • Therefore, there is need to deliver the goodness of oil in Non –oily (Non-Sticky) feel • The reason of oily feel is low spread ability on hair and scalp. • The slow / and low absorption is also the cause of oily feel. • The oil- blend should be formulated so that it gives the fast penetration ,better spread -ability and non greasing appreance on hair . • The formulation should be absorbed by the scalp/hair with gentle massage. • The actives delivered through the oil- blend should be able to penetrate fast ,hence deliver the benefit fast . • Currently ,use of LLP is in practice to make the light hair oil,which hinders the penetration of actives . • The new concept of light hair oil with above concept will provide the plat form for the hair and skin formulations with higher efficacy and better sensorial . • The Naturalness is achieved.