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Your First Choice Therapy in Seasonal Conjunctivitis & All forms of Rhinitis

Azelastine Eye Dops - Optilast. Your First Choice Therapy in Seasonal Conjunctivitis & All forms of Rhinitis. Azelastine is more than just an antihistamine. Azelastine inhibits allergic complaints and release of Leukotrienes in Rhinitis patients after allergen provocation.

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Your First Choice Therapy in Seasonal Conjunctivitis & All forms of Rhinitis

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  1. Azelastine Eye Dops - Optilast Your First Choice TherapyinSeasonal Conjunctivitis &All forms of Rhinitis

  2. Azelastine is more than just an antihistamine

  3. Azelastineinhibits allergic complaints and release of Leukotrienes in Rhinitis patients after allergen provocation

  4. Azelastine Reduces Symptoms & Leukotrienes in Early Phase Allergic Reactions after Allergen Challenge

  5. Azelastine Reduces Symptoms & Leukotrienes in Early-phase Allergic Reactions after Allergen Challenge (II)

  6. Azelastine Has Long-Lasting Anti-Inflammatory Effects in Late-phase in Allergic Reaction after Allergen Provocation

  7. “…Azelastine ophthalmic solution was effective for treating itching of the eye associated with allergic Conjunctivitis & was reported to be superior to the most recently used allergic Conjunctivitis medication by >50% of the patients.Azelastine was reported to work quickly & provided sustained relief when used twice daily in each affected eye.” Patients Evaluation of Azelastine solution in Allergic ConjunctivitisPoster presented at the 2004 AAAAI Annual Meeting, March 19-23, 2004 in San Francisco

  8. “…Therapy of experimentally induced allergic Conjunctivitis with Azelastine was highly effective, with an onset of action seen within 3 minutes & a duration of effect of at least 8 to 10 hours.” Evaluation of the Onset & duration of effect of Azelastine eye drops(0.05%) Vs placebo in Pts. With allergic conjunctivitis using an allergen challenge model.2000 by the American Academy of Ophthalmology ,107: 2152-2157

  9. Azelastine Eye Drops are already effective after three minutes

  10. Azelastine Eye Drops are effective for at least 12 hours

  11. Azelastine Eye Drops reduce the main Rhinoconjunctivitis symptoms

  12. Azelastine is more than just an antihistamine • Azelastine reduces allergic complaints and Leukotrienes • Azelastine reduces adhesion molecules, which attract inflammatory cells • Azelastine reduces the infiltration of inflammatory cells such as • neutrophils and eosinophils in early and late-phase reactions • TNFa & IL – 6 participate in the initiation of inflammation & acute phase reactions, while IL – 8 is a potent neutrophils chemo tactic molecule involved in inflammation

  13. Rhinolast can be used in all forms of allergic Rhinitis • To date it is the only FDAapproved substance for vasomotor Rhinitis • Azelastine can be used as s rescue medication in oral antihistamine non-responders No other substance for allergic Rhinitis offers such a broad clinical spectrum. Azelastine represents a first-line therapy for mild to moderate allergic Rhinitis

  14. Uses & Safety • Safe & effective for adults & children Rhinolast –6 Yrs & over, Optilast – 4 Yrs. & over • Rhinolast – Benzalkonium free formulation – no epithelial demage • Convenient twice daily administration • Side effect: irritation of nasal mucosa. A bitter taste may be experienced upon application Azelastine pharmacokinetic profile is perfect for thepatients’ needs

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