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IL-10, IL-6, and MMP-1 mRNA Release from Donor 4: Statistical Analysis and Implications

This study examines the release of IL-10, IL-6, and MMP-1 mRNA from donor 4 under specific conditions, revealing significant differences in expression levels. Key findings include IL-10 release measured in pg/ml with notable p-values (<0.001), highlighting the effect of different peptide conditions on cytokine release. Statistical analyses indicate meaningful variations in expression patterns for cytokines, providing insights into immune response mechanisms. Our results could have broader implications for therapeutic strategies in modulating immune responses.

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IL-10, IL-6, and MMP-1 mRNA Release from Donor 4: Statistical Analysis and Implications

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  1. Additional file 4 Morozov et al. 1600 A donor 4 1400 • p<0,05 IL-10 release [pg/ml] 1200 • p<0,001 1000 800 600 400 • p<0,001 • p<0,001 200 0 6A 2A wt gp 41 isu peptide mock 40 • P~1 B donor 4 • p<0,65 35 30 • p<0,001 25 IL-6mRNA 20 15 10 • p<0,001 5 0 isu peptide mock 6A 2A wt gp41 35 donor 4 C • p<0,3 30 • p<0,001 25 20 MMP-1 mRNA 15 10 • p<0,001 • p<0,001 5 0 mock isu peptide 2A 6A wt gp41 FCN1 % expression • p<0,3 • p<0,1 120 D donor 4 100 80 • p<0,001 60 40 • p<0,001 20 0 Isu peptide 6A wt gp41 mock 2A

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