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EMBASE 、 BA 数据库检索

EMBASE 、 BA 数据库检索. 一、光盘检索系统 WinSPIRS 简介 二、 Excerpta Medica Database (EMBASE) ** 三、其它 EMBSE 检索途径简介 四、 Biological Abstracts(BA) ** 五、 BIOSIS Previews 的检索方法. 重点：. 掌握 EMBASE 特征检索及其他各种字段。 熟悉疾病关联词、药物关联词。 熟悉 EMTREE 的组成。 熟悉 BA 的 Authority File 的构成 . 掌握其主要字段（ TS) 中包含的字段。 区别 BA,MEDLINE 与 EM.

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EMBASE 、 BA 数据库检索

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  1. EMBASE、BA数据库检索 一、光盘检索系统WinSPIRS简介 二、Excerpta Medica Database (EMBASE) ** 三、其它EMBSE检索途径简介 四、Biological Abstracts(BA) ** 五、BIOSIS Previews的检索方法

  2. 重点： • 掌握EMBASE特征检索及其他各种字段。 • 熟悉疾病关联词、药物关联词。 • 熟悉EMTREE的组成。 • 熟悉BA的Authority File的构成. • 掌握其主要字段（TS)中包含的字段。 • 区别BA,MEDLINE与EM

  3. WinSPIRS检索系统介绍 • 检索主界面(WinSPIRS 5.00) • 功能按钮 • 命令菜单 • 检索运算符 • 检索方法

  4. 功能按钮 检索式输入框 检索史区 检索记录显示区

  5. 功能按钮 • 按钮栏 • Database • Print • Download • Searches • Index • Thesaurus

  6. 其它功能按钮: • 检索区 • Search、Suggest • 检索史区 • Show、Retype、 Limits…、Clear… • 检索记录显示区 • Next Hit、Previous Hit • Brief Fields、Add to Search • 三个分栏显示图标

  7. 命令菜单 • 检索策略的保存与运行 • 可检索字段 • 标记记录 • 显示标记记录 • 参数设置 • 帮助 ……

  8. 截词符和通配符 Comput* computer,computor,computing… Wom?n woman,women…

  9. And Or Not • AND gastric and stasis [郁积] Retrieves records that contain both “gastric" and “stasis." • OR hepatitis B or hepatitis C Retrieves records that contain “hepatitis C" or “hepatitis D" • NOT dyspepsia not aged [消化不良] Retrieves records that contain “dyspepsia" , not concluding records that contain “aged"

  10. And Near With • AND saccharin and synthesis [糖精] Retrieves records that contain both "saccharin" and "synthesis." in the same record. • WITH family with stress Retrieves records that contain both "family" and "stress" in the same field. • NEAR blastula near embryo [囊胚] Retrieves records that contain both "blastula" and "embryo" in the same sentence.

  11. 检索途径和方法 • Search 检索 • 基本检索 • Suggest检索 • Limit检索 • 限定字段检索（可直接进行主题词检索） • 横向检索 • Index 检索 • “Change”字段索引词检索 • Thesaurus检索 • 单一主题词检索/扩展主题词检索 • 副主题词 (关联词)

  12. The Power of EMBASE + MEDLINE Combined!

  13. About EMBASE This bibliographic database features highly relevant information, much of which simply cannot be found elsewhere. Renowned for its comprehensive international coverage, EMBASE now contains more than 9 million records from 1974 to the present from over 4,000 journals; approximately 450,000 records are added annually. Over 80% of recent records contain full author abstracts.

  14. EMBASE 简介 • Excerpta Medica Database • 药理学，生物医学书目数据库 • 来源于110多个国家的4000种期刊 • 1974年至今共九百万条记录 • 年增记录445000条 • 最近出版的80%记录含著者文摘

  15. Features Coverage : • Drug Research, Pharmacology, Pharmaceutics, Pharmacy, Side Effects and Interactions, Toxicology • Human Medicine (Clinical and Experimental) • Basic Biomedical Sciences • Biotechnology, Biomedical Engineering and Instrumentation • Health Policy and Management, Pharmacoeconomics • Public, Occupational and Environmental Health, Pollution • Substance Dependence and Abuse • Psychiatry • Forensic Medicine • Alternatives to Animal Testing

  16. 学科范围 • 药物研究，药理学，药物副作用及相互作用 • 毒理学，人类临床试验药学 • 生物科学基础 • 生物技术、生物工程及生物仪器 • 卫生政策及管理 • 药物经济学 • 公共职业卫生与环境，污染与健康 • 药物依赖及成瘾性 • 精神病学 • 法医学

  17. Unique benefits: • Drug literature record access through chemical name, drug trade name or manufacturer name • Enhanced biotechnology, pharmacy and medical devices coverage • Medical device trade name and manufacturer names fields • Precise and reliable indexing using EMTREE, a hierarchically-ordered, synonym-controlled thesaurus—with more than 45,000 drug and medical indexing terms and 190,000 synonyms (incorporating all MeSH terms)

  18. EMBASE 特征: • 1900多种期刊与IM重复 • 美24.8%; 英13.2%; 德11.8%; 我国15种(0.26%) • 40%的记录与药物研究有关,1/3的记录与临床医学相关 • 药物“关联词”多，检索药物途径全面 • 有关药物字段多DR\EL\MN\RN\TN

  19. EMBASE 特征 • 通过药物商品名称，化学名称或制造者名称查找药物相关文献。 • 含医学设备商品名称，制造厂商名称字段。 • 四万二千条药物及医学索引词，十八万同义词（合并许多MESH主题词）

  20. EMBASE CD-ROM • Elsevier Science出版社—1989年 • 产品： EMBASE CD EMBASE Drugs & Pharmacology CD CANCER-CD EMBASE Specialties Series http://www.elsevier.nl/homepage/sah/spd/site/locate_embase.html

  21. EMBASE CD Description: Over 6 million abstracts and citations from 1980 to the present- over 4,000 biomedical journals are screened from 70 countries. Monthly updates will add approximately 34,000 new records. Important drug information not covered in other major biomedical databases EMTREE Thesaurus incorporating a user-friendly combination of EMTREE descriptors and medical MeSH terms

  22. EMBASE分类系统 • EMTREE 1988年开始使用 • EMCLAS 1974-1988年 EMBASE的分类系统， • EMTAGS 全面的索引分类体系，1998年停用

  23. EM CLASSIFICATION SYSTEM • EC(EMCLAS) EMBASE最早的主题分类体系，它的一级分类号用来标引记录，用户可以用EC字段用来检索相应记录。 • 药物EC 药物EC标题（37）1990年停用，表现为数据库的EL字段中的药物11位数字。

  24. EM CLASSIFICATION SYSTEM • EMCLAS - Section Numbers and Headings 1 Anatomy, anthropology, embryology and histology2 Physiology3 Endocrinology… 37 Drug EMCLAS 3738 Adverse reactions titles39 Pharmacy… 52 Toxicology151 Mycobacterial diseases (1984-1988) 完整列表可见EMBASE帮助系统

  25. EM CLASSIFICATION SYSTEM • EMTREE • 受控词汇 • 等级排列 • 树状结构 （15方面 115分支 再次细化 各类的范围注释） Anatomical concepts (facet A) Physical diseases, disorders and abnormalities (facet C) Chemicals and drugs (facet D) • 字顺索引(上下位词，相互参照）（手工版本）

  26. EMTREE • 45,000药物医学术语 • 10,000个代码 • 190,000同义词包括各种药物名称的变化形式和NLM的MeSH主题词

  27. EMTREE • EMTREE Stomach bleeding Stomach hemorrhage(首选词）

  28. EMTREE • EMTREE中检索时，系统将同时检索: Major Medical Descriptors (DEM), Minor Medical Descriptors (DER), Major Drug Descriptors (DRM), and Minor Drug Descriptors (DRR)字段（2000年以后）。

  29. EMTREE • EMTREE取词规则 *自然词语序e.g. acute granulocytic leukemia (急性粒细胞性白血病 not leukemia, acute granulocytic)*单数名词形式e.g. stomach tumor (not gastric tumors)*美式写法优先于英式写法 e.g. fetus (not foetus) *少数的缩写词e.g. nuclear magnetic resonance (“nmr” is a synonym) *希腊字母拼出e.g. alpha adrenergic receptor *元标点，无连字符，省略号，逗号，化学物质除外。 e.g. down syndrome; 4 ethyl 2,5 dimethoxyamphetamine (二甲苯异丙胺）[连字符用于精确检索]*可使用专深词汇e.g. acute lymphocytic leukemia (as well as the broader term "leukemia")

  30. EMTREE • EMTREE的作用 查找扩展词，防止漏检 浏览扩展词的下位词 查找标引首选词 通过term information确定检索词

  31. EMTREE 示例： Hay fever(花粉热) respiratory tract allergy allergic pneumonitis allergic rhinitis asthma hay fever house dust allergy nose allergy pollen allergy

  32. EMTREE • EMTREE药物索引 EMTREE包括根据世界卫生组织国际命名标准而确定的药物及化学物质首选名称，其中，药物一般名称包括，实验室代码，商品名称，各种拼写，外来名称，化学复合物名称及MESH主题词 propranolol（DOCITON和INDERAL) paracetamol (首选词） acetaminophen and 4 acetamidophenol 数据库中DRM和DRR字段包括标记这些首选药物和化学物质名称，商品名称在TN字段

  33. EMTREE EMTREE - Disease Link and Drug Link Terms Disease link terms and drug link terms are controlled terms frequently used with a medical or drug index term to indicate precise associations. They have been used in EMBASE since 1988. Search for these associations by using a hyphen between the index term and the link term or as independent terms. For example, the search cardiovascular-surgery in su retrieves records that are about surgical aspects of cardiovascular.

  34. Disease Link Terms ComplicationCongenital disorderDiagnosisDisease ManagementDrug resistance (began 1996)Drug therapyEtiology 14个疾病关联词 Epidemiology PreventionRadiotherapyRehabilitationSide effectSurgeryTherapy EMTREE

  35. EMTREE Disease Link Terms 示例： Parkinson's disease+surgery 1988以前： parkinson disease and surgery（98） 现在： Parkinson- disease/surgery(62)

  36. Drug Link Terms 17个主药物关联词 Adverse drug reaction Clinical trialDrug administrationDrug analysisDrug combinationDrug comparisonDrug concentrationDrug developmentDrug doseDrug interaction Drug therapy Drug toxicityEndogenous compoundPharmaceuticsPharmacoeconomicsPharmacokineticsPharmacology 47个分支药物关联词 Buccal drug administrationEpidural drug administrationInhalational drug administration…… EMTREE

  37. EMTREE • 示例： 1.losartan (as descriptor) 545 2.losartan (link) drug combination 40 3 .losartan(link)drug comparison 125

  38. 记录样例 TI - TITLE: Somatic mutation theory of carcinogenesis: Why it should be dropped and replaced AU - AUTHOR(S): Sonnenschein-C; Soto-AM AD - ADDRESS OF AUTHOR: C. Sonnenschein, Dept. of Anatomy and Cell. Biology, Tufts University School of Medicine, Boston, MA 02111, United States SO - SOURCE (BIBLIOGRAPHIC CITATION): MOL-CARCINOG. Molecular- Carcinogenesis. 2000; 29/4 (205-211) CO - CODEN: MOCAE IS - ISBN/ISSN (INTERNATIONAL STANDARD NUMBERS): 0899-1987 PY - PUBLICATION YEAR: 2000 CP - COUNTRY OF PUBLICATION: United States LA - LANGUAGE OF ARTICLE: ENGLISH LS - LANGUAGE OF SUMMARY: ENGLISH AB - ABSTRACT: The somatic mutation theory of carcinogenesis has been the dominant force driving cancer research during the 20th century. In brief, it …

  39. 记录样例 DEM - MAJOR MEDICAL DESCRIPTORS: somatic-mutation; carcinogenesis- DER - MINOR MEDICAL DESCRIPTORS: cancer-research; gene-mutation; cell-proliferation; metazoon-; cell-interaction; stroma-; neoplasm-; tumor-cell; human-; nonhuman-; article-; priority-journal DRR - MINOR DRUG DESCRIPTORS: carcinogen- EC - EMCLAS CLASSIFICATION: Cancer- (16); Human-genetics (22) PT - PUBLICATION TYPE: Journal DT - DOCUMENT TYPE: Article RF - NUMBER OF REFERENCES: 49 AN - ACCESSION NUMBER: 2001024129 UD - UPDATE CODE: 20010201

  40. EMBASE主要字段说明 AB Abstract AD Address of Author AN Accession Number AU Author(s) BT Book Title CD Conference Details CF Conference Name CO CODEN CP Country of Publication CT Conference Proceedings Title DE Medical Descriptors（99年以前）（dem,der) DM Device Manufacturers Names DN Device Trade Names DT Document Type DR Drug Descriptors(99年以前）（drm,drr)

  41. EMBASE主要字段说明 EC EMCLAS Classification ED Editor(s) EL EMCLAS Drug Classification EML E-Mail Address IS ISBN/ISSN (International Standard Numbers) LA Language of Article LS Language of Summary MN Manufacturer Names MS Molecular Sequence PB Book Publisher PI Publisher Item Identifier

  42. EMBASE主要字段说明 PT Publication Type PY Publication Year RF Number of References RN CAS Registry Number RP Report Number* SO Source (Bibliographic Citation) SU Subjects** TI Title TN Trade Names TO Original (Non-English) Title TS Titles** UD Update

  43. EMBASE主要字段说明 举例： diabetes-mellitus in DEM kidney-failure in der penicillin-derivative in drm 注意连字符的使用： diabetes mellitus in dem与 diabetes- mellitus in dem的区别???

  44. EMBASE限制字段 EMBASE Accession Number (AN)CODEN (CO)Country of Publication (CP)EMCLAS Classification (EC)EMCLAS Drug Classification (EL)ISBN/ISSN (International Standard Numbers) (IS)Language of Article (LA)Language(s) of Summary (LS)Publication Type (PT)Publication Year (PY)Number of References (RF)Update (UD)

  45. EMBASE限制字段 举例： french in la or la=french py<1991 orthopedic in ec [整形外科的] ec=33 ud=19980125-19980401

  46. EMBASE检索示例 • 查找中草药治疗高血压的综述文献 1) hypertension 2) and herbal medicine 3) and review in dt

  47. EMBASE检索示例 • 查找儿童尿道感染的流行病学方面的信息 1) urinary tract infection 2) and child* 3) and epidemiology in su

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