Partnerships in Technology Transfer: The NIH Experience

1. Partnerships in Technology Transfer: The NIH Experience Luis A. Salicrup, Ph.D. Senior Advisor for International Activities Office of Technology Transfer National Institutes of Health U.S. Department of Health & Human Services FLC Meeting September 14, 2005

2. NIH Mission To uncover new knowledge that will lead to improved public health

3. National Institutes of HealthBasic Biomedical Research in Support of the Public Health • Funding • Training • Basic Research • Clinical Trials • Inventions • Policies

4. Humanitarian Objectives Globalization of Health Problems and their Relevance to Domestic Health Economic Development and Political Stability Importance of Global Health Research

5. Relevance of Technology Transfer to Institutions in Developing Countries Innovation of all types National, regional and global needs Reduction of the burden of disease worldwide 10/90 GAP

6. New Trends in Health Entities in LDCs • Increase in public-private partnerships • Developing countries (India, Brazil, China, South Africa) strengthening investments in biotechnology research of endemic and neglected diseases • Developing country institutions entering various types of R&D agreements for transferring technologies

7. Partners for Global Health NIH OTT currently active exploring ways to enhance the process of transferring technologies to institutions in: • Asia • Latin America • Africa • Eastern Europe

8. HIV/AIDS Tuberculosis Malaria Dengue Pertussis Meningitis Rotavirus Typhoid Fever Cancer Diabetes Medical Devices & Animal Models Collaborative work with institutions in developing countries has revealed needs and opportunities for transfer of NIH technologies related to:

9. Capacity Building at NIH-OTT Information Access Combined initiative by NIH-OTT and U.S. academic institutions Database of technologies for neglected diseases Resource tool for managers and scientists in developing countries

10. International Technology Transfer Internship Program Aimed to train Scientists and Managers Provide key exposure & practical experience Long & Sustainable Process Partnerships with several institutions in Asia, Africa, Latin America, and Eastern Europe

11. Program Objectives • Learn different aspects of IPM • Assessment & Commercialization of Technologies • Exposure to practical aspects of negotiation license agreement • Enhance understanding IPR Policy • Understand Global Challenges • Clinical Trials • Capacity Building • Public-Private Partnerships

12. Training Implementation Rotations will depend on the needs of partners • Different OTT Divisions and/or • NIH’s ICs’ Offices of Technology Development • U. S. Academic Institutions Mentors (sustainable relationship) First Phase: Staff from institutions in China, Brazil, South Africa, India, Argentina, Hungary

13. Additional Training  Participation in FAES/NIH TT Course  Participation in Seminars at OTT & NIH  Workshops in the field--Partners  Relevant courses & guidance at U.S. Universities  Participation in relevant professional meetings (e.g. AUTM, FLC, BIO)

14. Lessons Learned Participating institutions should have • Some level of R&D capabilities • Clear objectives to address national and regional public health needs • Need to work with public and private institutions in those countries • Comprehensive, multidisciplinary, sustainable training approach • Next Steps: Evaluation/Needs Assessment

15. RESEARCH & DEVELOPMENT INNOVATION HEALTH TECHNOLOGIES CAPACITY BUILDING IN DEVELOPING COUNTRIES POVERTY REDUCTION & POTENTIAL ECONOMIC GROWTH ACCESSIBLE DRUGS, DIAGNOSTICS, THERAPEUTICS REDUCTION OF DISEASE BURDENS (INFECTIOUS & CHRONIC)

16. NIH CONTACTS • NIH http://www.nih.gov • OTT http://ott.od.nih.gov • TT Training http://tttraining.od.nih.gov • Clinical Trials http://clinicaltrials.gov E-mail: salicrul@mail.nih.gov