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Electrospinning Nanofibers for Scaffolding

Electrospinning Nanofibers for Scaffolding. By: Dan Tamayo. What are Electrospun Nanofibers ?. Electrospun Nanofibers are polymer solutions that are pumped through a syringe They form an ultrafine fiber that are layered on top of each other to form a mesh

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Electrospinning Nanofibers for Scaffolding

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  1. ElectrospinningNanofibers for Scaffolding By: Dan Tamayo

  2. What are ElectrospunNanofibers? • Electrospun Nanofibers are polymer solutions that are pumped through a syringe • They form an ultrafine fiber that are layered on top of each other to form a mesh • This mesh can be used to culture and cultivate cells as a scaffold in tissue engineering

  3. How it’s Done http://www.jove.com/video/2494/electrospinning-fundamentals-optimizing-solution-and-apparatus-parameters 2:23

  4. Finished Nanofiber Scaffold

  5. Uses • Used for tissue engineering scaffolding • Can be used to deliver medication

  6. History of Electrospinning • 1902- Electrospinning was first discovered by Marley and Cooley • 1934- The apparatus was designed and patented • 1940- The design was perfected and a new apparatus was patented, this is the apparatus and technique we use today

  7. State of the Art Technology • Today there are ways that nanofibers can be electrospun while infused with medication. While these nanofibers biodegrade, the medication is evenly released throughout the body.

  8. Limitations • Research • Difficult to do

  9. Future • We will be able to make scaffolding out of materials and chemicals that mimic human proteins and tissues identically. • The optimal scaffold will be found to make cells grow, mature and direct cell migration to the best of their ability.

  10. Work Cited • Meng, Z & Zu, X (2011) Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system. Colloids and Surfaces B: Biointerfaces. 84 (1) 97-102 • ChinweNwachukwu, C (2010) Electrospinning protein nanofibers to control cell adhesion. University of South Florida Scholar Commons. 55 (3) • Subbiah, h & Bhat, G (2005) Electrospinning of nanofibers. Applied Polymer Science. 96 (2) 557-569

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