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Grantsmanship 101: What They’ll N ever Tell You!. Todd K. Rosengart, MD Professor and Chairman DeBakey Bard Chair of Surgery The Michael E. DeBakey Department of Surgery Baylor College of Medicine March 8, 2013. Getting Ready: Are Your Ready to Rumble?.
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Grantsmanship 101: What They’ll Never Tell You! Todd K. Rosengart, MD Professor and Chairman DeBakey Bard Chair of Surgery The Michael E. DeBakey Department of Surgery Baylor College of Medicine March 8, 2013
Getting Ready: Are Your Ready to Rumble? • Know the literature, know the field • Use your own publications as a foundation • Be at an inflection point in your investigations • Gather team and resources in hand
The Title: A Rose by Any Other Name… • 81 characters to get it done… • Active and descriptive • Page turner • “Method for Cardiac Cell Reprogramming” • OR • “Cellular Reprogramming to Induce Cardiac Regeneration”
Specific Aims: Where It’s At! • Spend up to 40% of time on specific aims page • Big, impactful idea in context (four sentences) • Clinical translation (one to two sentences) • Hypothesis driven • Three aims – progressive and integrated
Innovation • How is this different than prior art • Approach • Technology or metrics • Output • Be firm but humble • This ain’teasy…
Faculty and Personnel • Personal statement – use it! • Expertise to do the project • Funding record • Areas of experience • Not too many or too few • Role for consultants
Budget • Nothing wrong with modular • Don’t overdo it… • Doesn’t “count”, but….
Research Plan • Match plan to aims • Goldilocks: Don’t be too ambitious, or too incremental • Explain what you plan to do (overview), explain why you are • going to do what you plan (rationale), explain what you are • doing (experimental method), explain what you did (analysis) • Data analysis and alternatives • No fishing expeditions! • What can go wrong?? • Show you know the field (especially of experts in the room) • Timeline – can you get it done?
Research Plan • Make it clear and easy to read! • Bold print summary of key points • Italics and underline less effective (my opinion) • Hypothesis flow-diagrams • Avoid: • Jargon • Excessive data • Abbreviations • Minutiae of experimentation • Uninterpretable figures and tables
Research Plan: Preliminary Data • Make it clear: you can do what want to do! • Have you (almost) already done it? • Drive power analysis and • recruitment feasibility
Know Your Study Section • Know your reviewers • Expectations vary • Make it easy for an advocate…..
In Their Own Words – NIH Tips for Young Investigators • Have a good idea! • Establish your independence as an investigator. • Generate preliminary data. • Enlist collaborators and include letters that clearly spell out collaborations. • Look at successful proposals of colleagues in your field. • Convey your confidence and enthusiasm for the project. • Do your homework - know the literature, issues, questions and controversies. • Place your work in perspective. • Cite others. If there are two camps, make sure you cite both sides. • Make your priorities clear. Provide a timeline. • Be focused. • Discuss potential problems and pitfalls. Describe alternate strategies. • Carefully consider your funding needs. • Use a clear and concise writing style. • Proofread! No typographical errors, misspellings or sloppy formatting. • Critique your own proposal. • Have others read your final draft, as well.