Alagille Syndrome Market Size Worth USD 601.56 Million in 2030

1. Alagille Syndrome Market Size Worth USD 601.56 Million in 2030 www.emergenresearch.com Increasing prevalence of Alagille Syndrome is one of the key factors driving Alagille Syndrome market revenue growth

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5. Market Summary The global Alagille Syndrome market size was USD 361.89 Million in 2021 and is expected to register a revenue CAGR of 5.8% during the forecast period, according to latest analysis by Emergen Research. Increasing prevalence of alagille syndrome, rising number of clinical studies and trials in the field of alagille syndrome-based treatments, and introduction of novel and advanced diagnostic platforms for early diagnosis are crucial factors driving market revenue growth. Alagille syndrome is a genetically inherited condition that is similar to other forms of liver disease frequently seen in infants and young children. According to the National Institute of Diabetes and Digestive and Kidney Diseases, Alagille Syndrome affects one in every 30,000 live newborns. Clinically, Alagille Syndrome shows as a variety of phenotypes, but is commonly distinguished by five distinct symptoms, impaired bile flow, congenital heart disease, bone issues, a thickening of the crease of eyelid, and particular facial characteristics. The diagnostics can be supported by genetic testing. ALGS is a multisystem disorder with a wide range of clinical variability, from preclinical symptoms to modestly abnormal liver enzymes, a heart issue, butterfly vertebrae, and posterior embryotoxicity. In addition to supporting biomarker tests and molecular genetic analysis, clinical diagnosis of Alagille syndrome requires proof of a lysosomal acid alpha-glucosidase enzyme deficiency, which can be confirmed in dried blood spots or liquid blood samples. Alagille syndrome may be diagnosed by means of other tests in addition to a liver biopsy, which include eye exams, spine x-rays to look for distinctive changes such as butterfly vertebrae, abdominal ultrasounds of hepatobiliary tree (including the liver, pancreas, gall bladder, and spleen) to look for abnormalities or rule out other conditions, and blood tests to assess liver function and find fat-soluble vitamin deficiencies. Personalized molecular screening and genetic testing of those who are at risk can result in early diagnosis and treatment beginning, potentially improving clinical results of Alagille syndrome patients. . www.emergenresearch.com

6. Market Summary • Further key findings from the report suggest • The genetic testing segment accounted for a significant revenue share in 2021. Genetic testing is a preferred approach for validating diagnosis of alagille syndrome (ALGS), which is brought on by genetic changes in the Jagged 1 (JAG1), Notch 2 (NOTCH2), or 20p12 chromosomal deletion. Nearly 95% of patients with clinical symptoms and an ALGS-related mutation are found through accurate genetic testing. This procedure, carried out by a medical expert in a lab setting, entails cellular DNA extraction and analysis to find genetic abnormalities that might be the disease's etiology. Genetic testing can help to predict patient outcomes, recurrence risk, and medical care by identifying gene mutations related to ALGS. Prenatal genetic testing (DNA samples taken during pregnancy) or preimplantation genetic testing (DNA samples taken from embryos created through in vitro fertilization) can aid in early detection of ALGS in fetus if one or both parents have the condition. These are major factors driving growth of this segment. • The hospitals segment accounted for a significant revenue share in 2021. Many hospitals are working on novel and improved ways to facilitate in the early detection of alagille syndrome, with the goal of quickly transferring patients with mild symptoms to expert centers. Patients would be able to be properly tested and diagnosed, allowing them to begin treatment as soon as possible. In addition, hospital doctors and medical specialists are providing individualized methods for all forms of alagille syndrome and additional supportive drugs that address the condition's symptoms and problems. • The Europe market accounted for a moderate revenue share in 2021. Experimental drugs prepared for alagille syndrome have been gaining an increasing number of approvals in the recent years.. • Request Free Sample Copy@ https://www.emergenresearch.com/request-sample/1209 www.emergenresearch.com

7. Market Summary • Emergen Research has segmented the global alagille syndrome market based on diagnostic method, treatment type, treatment centers, and region: • Diagnostic Method Outlook (Revenue, USD Million; 2019-2030) • Genetic Testing • Liver Biopsy • Heart and Blood Vessel Tests • X-ray Imaging • Abdominal Ultrasound • Kidney Function Tests • Treatment Type Outlook (Revenue, USD Million; 2019-2030) • Drug Medications • Ileal Bile Acid Transporter (IBAT) inhibitors • Ursodeoxycholic Acid • Cholestyramine • Rifampicin • Late Stage Pipeline Drugs • Others • Read More@ https://www.emergenresearch.com/industry-report/alagille-syndrome-market

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