1 / 1

Exploring Stress Response Mechanisms in Epithelial Cells: Insights from C. elegans

This study investigates the underlying mechanisms of stress response in epithelial cells, focusing on key genetic players involved in the antimicrobial response and cellular stress adaptation in *Caenorhabditis elegans*. We examine the roles of genes like DAF-16, SMA-3, and their pathways, including the PIP3/AKT signaling axis, in the context of cellular resilience. The findings contribute to our understanding of how intestinal lumen bacteria interact with host responses, highlighting the intricate balance between stress management and immune function.

sasha-whitaker
Télécharger la présentation

Exploring Stress Response Mechanisms in Epithelial Cells: Insights from C. elegans

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. ? DAF-18 TRX-1 PDK-1 PIP-2, PIP3 AKT-1/AKT-2 Stress Response CTL-2 SOD-3 Antimicrobial Response LYS-7 SPP-1 CLK-1 Hypodermis TOL-1 INS-7 INS-1 Pseudocoelom DBL-1 A B C D DAF-2 SMA-6 DAF-4 Epithelial cell AGE-1 TIR-1 NSY-1 SMA-3 SMA-2 SMA-4 SEK-1 DAF-16 PMK-1 SMA-3 SMA-2 DAF-16 SMA-4 Antimicrobial Response PHM-2 LYS-1 Intestinal lumen Bacteria Pharynx Epithelial cell

More Related