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CASO HOSPITAL EL ESCORIAL Dra. Moreno, Dra. Elices

REUNIÓN TERRITORIAL DE LA SEAP. CASO HOSPITAL EL ESCORIAL Dra. Moreno, Dra. Elices. Mujer 32 años AP: Alergia (polen, látex) Julio: Endometritis. Ecografía : Mioma submucoso-intramural con necrosis Actual (Octubre): Miomectomía. MACROSCOPIA . Ovoideo Dimensión: 5 x 4 x 3,5 cm.

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CASO HOSPITAL EL ESCORIAL Dra. Moreno, Dra. Elices

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  1. REUNIÓN TERRITORIAL DE LA SEAP CASO HOSPITAL EL ESCORIAL Dra. Moreno, Dra. Elices

  2. Mujer 32 años • AP: • Alergia (polen, látex) • Julio: Endometritis. Ecografía: Mioma submucoso-intramural con necrosis • Actual (Octubre):Miomectomía

  3. MACROSCOPIA • Ovoideo • Dimensión: 5 x 4 x 3,5 cm. • Peso: 29 grs. • Bien delimitado • Consistencia elástica blanda • Coloración rosado-anaranjada

  4. DIAGNÓSTICO DIFERENCIAL • Mtx. Ca. Renal:CQ, Vimentina, EMA • L. epitelioide de cls. claras: desmina, actina • Tr. estromal endometrial: CD10 • PEC-oma: HMB-45 • Tr. de cls. granulares: S-100

  5. POSITIVOS Vimentina Desmina Actina CD68 NEGATIVOS Citoqueratina AE1-AE3 EMA CD10 HMB-45 S-100 Factor VIII CD34 ESTUDIO IHQ

  6. Vimentina

  7. AE1-AE3

  8. Actina

  9. Desmina

  10. CD68

  11. CD68

  12. Ki-67

  13. DIAGNÓSTICO LEIOMIOMA EPITELIOIDE DE CÉLULAS CLARAS

  14. LEIOMIOMA Y CD68 Cambio granular por acúmulo de lisosomas • Oliva E et al.International Journal Of Gynecological Pathology, 2002;21:48-55. • Roncaroli F et al.Human Pathology, 1994;24:1260-3. • Mentzel T et al. Histopathology, 1994;24:223-31. • Tsang WY et al. Histopathology, 1992;21:84-6.

  15. LEIOMIOMA EPITELIOIDE • Subvariantes:Leiomioblastoma, de cls claras, plexiforme • Potencial incierto: • 6 cm • Necrosis • Atipia moderada-severa • Mitosis: 2-4/10 CGA

  16. ¡TODOS CONTENTOS!

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