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Figure 2S. B. A. p-Akt. Akt. -. +. -. +. Ascites. -. -. +. +. DGPP 100 ng/ml). C. D. p-Akt. Akt. PTX untreated. PTX (100 ng/ml). -. +. -. +. Ascites. -. -. +. +. PTX 100 ng/ml).
Figure 2 Panel A. **. *. ng/ml. **. **. **. **. **. ng/ml. Figure 2 Panel B. *. *. *. *. *. ng/ml. *. *. *. *. *. *. ng/ml.
12. 10. 8. 6. [BMP9] ng/ml. 4. 2. 0. Healthy donors. HHT donors. Fig 4. A. 2. Serum. Plasma. Luciferase activity (arbitrary unit). 1. 0. Untreated. Donor 1. Donor 2. Donor 3. Donor 4. B. Pooled human serum concentration = 7.5 ± 0.6 ng/ml. 2. Luciferase activity
A. B. Colo 205. MDA MB231. MDA MB231. Colo 205. 16. 50. 90. 16. 45. 80. 14. 14. 40. 70. 12. 12. 35. 60. 10. 30. 10. 50. 25. 8. 8. 40. 20. 30. 6. 6. 15. 20. 4. 4. 10. 10. 5. 2. 2. 0. 0. 0. 0. 0,0001. 0,1. 100. 100000. 0,001. 0,1. 10. 1000. 0,01.
A). B). C). *. Concentration (ng/ml). Circulating PMN (% 0 min). Circulating PMN (% 0 min). *. *. Chemokine. Time after KC i.v. (min). Time after KC i.v. (min).
*. *. Insulin secretion (ng/ml). Glucose (mM) 3 20 3 3 3 3 H 2 O 2 ( m M) - - 1 10 - -HNE (10 m M) - - - - - + SIN-1 (200 m M) - - - - - +.
Measured Urinary Midkine & HAI-1 Concentrations and Calculated Contributions from Haematuria. Blue bars = measured concentration Red bars = calculated contribution from haematuria*. Urinary midkine (ng/ml). Controls. Controls. MIBC. MIBC. NMIBC. NMIBC. Urinary HAI-1 (pg/ml).