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Statistical issues in QTL mapping in mice

Statistical issues in QTL mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Outline. Overview of QTL mapping The X chromosome Mapping multiple QTLs Recombinant inbred lines Heterogeneous stock and 8-way RILs.

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806 views • 61 slides

length

natural group. morphology. length. colour. shape. ratio. width. venation. multivariate analysis. chromosome number. hairs. number. phenotype. genotype. crossability. stems. anatomy. leaves. flowers. secondary chemistry. UPGMA. embryology. parsimony. RAPDs. chloroplast. PCR.

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414 views • 21 slides

molecular revolution

molecular revolution. The first molecular markers: allozymes. Allozymes Enzymes that diifer in amino acid sequence yet catalyze the same reaction -visible as a band on a gel -may exist at several gene loci Isozyme: allelic form of allozyme (same locus). +. enzyme. Visible

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233 views • 8 slides

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Statistical issues in QTL mapping in mice

length

molecular revolution