'Abc dlbcl' diaporamas de présentation

Germinal Centers and Lymphomagenesis

V(D)J Recombination. IgV hypermutation. Immature B-cells. Germinal Center B-cells. Memory B-cells. Ag. B-CLL. Plasma cells. Bone Marrow. Mantle. Germinal Center. ALL. MCL. BL FL DLBCL. MM. Apoptosis. Germinal Centers and Lymphomagenesis.

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Gene Expression Profiling and Molecular Diagnosis of B-Cell Lymphomas:

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Wilson WH et al. Proc ASH 2012;Abstract 686.

The Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib (PCI-32765), Has Preferential Activity in the ABC Subtype of Relapsed/Refractory De Novo Diffuse Large B-Cell Lymphoma (DLBCL): Interim Results of a Multicenter, Open-Label, Phase 2 Study. Wilson WH et al. Proc ASH 2012;Abstract 686.

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RE Davis et al. Nature 463 , 88-92 (2010) doi:10.1038/nature08 638

CD79A and CD79B ITAM mutations in ABC DLBCL. RE Davis et al. Nature 463 , 88-92 (2010) doi:10.1038/nature08 638.

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M Compagno et al. Nature 000 , 1-5 (2009) doi:10.1038/nature07968

The NF- k B pathway is active in ABC-DLBCL and in a smaller fraction of GCB-DLBCL. M Compagno et al. Nature 000 , 1-5 (2009) doi:10.1038/nature07968.

105 views • 1 slides