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Entereg ® ( Alvimopan) Capsules Adolor Corporation (Non-Clinical Findings)

Entereg ® ( Alvimopan) Capsules Adolor Corporation (Non-Clinical Findings)

Entereg ® ( Alvimopan) Capsules Adolor Corporation (Non-Clinical Findings) . Tamal K. Chakraborti, Ph.D. Pharmacologist United States Food and Drug Administration Center for Drug Evaluation and Research Division of Gastroenterology Products. Non-Clinical Studies. Pharmacology

By andrew
(397 views)

Propionic acid derivatives

Propionic acid derivatives

Propionic acid derivatives. Ibuprofen, naproxen, fenoprofen , flurbiprofen , oxaprozin ,→ anti-inflammatory, analgesic, and antipyretic.

By jamuna
(732 views)

Metabolite of antipsychotic drug  DA antagonism 

Metabolite of antipsychotic drug  DA antagonism 

Metabolite of antipsychotic drug  DA antagonism  > suitable for depression in psychotic patients.  Parkinsonism Amenorrhea- galactorrhea Tardive dyskinesia. Side Effects of Tricyclic Antidepressants. !!!. TCAs.

By thimba
(118 views)

Moderate Sedation/ Analgesia (Conscious Sedation)

Moderate Sedation/ Analgesia (Conscious Sedation)

Moderate Sedation/ Analgesia (Conscious Sedation). Anuradha Patel M.B.B.S., M.D., D.A., F.R.C.A. ( I ), D.A.B.A. Assistant Professor, Department of Anesthesiology and Perioperative Medicine UMDNJ, Newark. Introduction.

By leanna
(339 views)

P roject :Medicines

P roject :Medicines

P roject :Medicines. Name : Xiang le Huai Kang Sadid a nd R emus. Creator of Penicillin. The person who created penicillin is Alexandre Fleming.(1881-1955) His father is a farmer. Alexandre Fleming is born in Scotland. His family move to Scotland to London.

By hovan
(74 views)

Key Pharmacokinetic Concepts – Single Dose and Steady State Drug Administration

Key Pharmacokinetic Concepts – Single Dose and Steady State Drug Administration

Key Pharmacokinetic Concepts – Single Dose and Steady State Drug Administration. Pankaj B. Desai. Ph.D. Professor of Pharmacokinetics and Biopharmaceutics Director, Drug Development Graduate Program. Morning Agenda: Wake Up and Smell the Coffee (Cytochrome P450 1A2 Substrate).

By rich
(288 views)

DC beads loaded with Irinotecan : precilinical in-vitro & in-vivo evaluation

DC beads loaded with Irinotecan : precilinical in-vitro & in-vivo evaluation

DC beads loaded with Irinotecan : precilinical in-vitro & in-vivo evaluation. T de Baere. Bench top Animal model. Colorectal cancer chemotherapy. % response rate. FOLFIRI. FOLFOX. LV5FU2. 5FU-FA. 55 %. 55 %. 5 FU. 25 %. 20 %. 10 %. Sytemic therapy.

By goro
(134 views)

Use of PPIs during Clopidogrel Therapy

Use of PPIs during Clopidogrel Therapy

Use of PPIs during Clopidogrel Therapy. Andrew N. Schmelz, PharmD Post-Doctoral Teaching Fellow Dept of Pharmacy Practice Purdue University February 26, 2009. Objectives. Describe the conversion of clopidogrel to its active metabolite Rank PPIs in regard to 2C19 metabolism

By locke
(136 views)

Anxiolytic sedatives (Minor tranquilizers)

Anxiolytic sedatives (Minor tranquilizers)

Anxiolytic sedatives (Minor tranquilizers) Anxiety is a sense of apprehensive expectation. Anxiety may be helpful e.g. anxiety before students examination but too much anxiety , however, can be deleterious due to it interferes with normal functioning

By melvyn
(767 views)

Bioprecursors

Bioprecursors

Bioprecursors. Bioprecursors result from a molecular modification of the active principle itself. This modification generates a new compound, able to be a substrate for the metabolizing enzymes (often, oxidation and reduction). The metabolite being the expected active principle.

By ruth-baldwin
(51 views)

The Inflammatory Response

The Inflammatory Response

Nonsteroidal Anti-inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout Dr. Florencia D. Munsayac. The Inflammatory Response. 3 Phases of Inflammation: Acute Inflammation The Immune Response Chronic Inflammation.

By gwenllian-baker
(348 views)

Pharmacokinetics: Bioavailability

Pharmacokinetics: Bioavailability

Pharmacokinetics: Bioavailability. Asmah Nasser, M.D. The fraction of the administered dose reaching the systemic circulation in its chemically unchanged form. Labelled as “F” Bioavailability of a drug administered IV: 100%

By clinton-pierce
(263 views)

Cytochrome system and drug metabolism

Cytochrome system and drug metabolism

Cytochrome system and drug metabolism. Dr.Abdul latif Mahesar. CYTOCHROME SYSTEM. &. DRUG METABOLISM. ILOs. Revise the intent(purpose) of drug metabolism and its different phases Define the role of cytochrome system in relation to drug metabolism

By iona-daugherty
(591 views)

Anthelmintics SCHISTOSOMIASIS

Anthelmintics SCHISTOSOMIASIS

Anthelmintics SCHISTOSOMIASIS. Alia Alshanawani Pharmacology Dep, Medical College; KSU. TREMATODES also called as flukes are leaf shaped flat worms characterized by ! tissues they infect as parasite: Lung / Liver / Intestinal / Blood FLUKES. Schistosomiasis

By jmcwhorter
(4 views)

Cardiotropic Drugs

Cardiotropic Drugs

Cardiotropic Drugs. Cardiotropic Drugs. used for Congestive Heart Failure and for Cardiac Arrhythmia. I. Digitalis Glycosides. Digoxin Digitoxin. Digoxin. Half-life 35 – 40 h Therapeutic Range 0.5 – 2 ng/mL Toxic Level >2 ng/mL Mechanism of Action

By klewis
(3 views)

Treatment of Respiratory Tract Infections

Treatment of Respiratory Tract Infections

Treatment of Respiratory Tract Infections. Prof. Mohammad Alhumayyd Dr. Aliah Alshanwani. Objectives of the lecture. At the end of lecture, the students should be able to understand the following: The types of respiratory tract infections (RTI) The antibiotics that are commonly used

By diannam
(3 views)

Treatment of Respiratory Tract Infections

Treatment of Respiratory Tract Infections

Treatment of Respiratory Tract Infections. Prof. Mohammad Alhumayyd Department of Pharmacology. Objectives of the lecture. At the end of lecture , the students should be able to understand the following: The types of respiratory tract infections The antibiotics that are commonly used

By bspriggs
(1 views)

Treatment Of Respiratory Tract infections

Treatment Of Respiratory Tract infections

Treatment Of Respiratory Tract infections. Prof. Azza ELMedany Department of Pharmacology Ext. 52412. Objectives of the lecture. At the end of lecture , the students should be able to understand the following: The types of respiratory tract infections The antibiotics that are commonly used

By stokesb
(15 views)


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