'Allelic variants' diaporamas de présentation

700 views • 54 slides

From biomedical informatics to translational research

Olivier Bodenreider Lister Hill National Center for Biomedical Communications Bethesda, Maryland - USA. Kno.e.sis Wright State University, Dayton, Ohio May 27, 2009. From biomedical informatics to translational research. Outline. Translational research Enabling translational research

818 views • 47 slides

Metabolism - Biotransformation

Metabolism - Biotransformation. Supplementary readings: Casarett and Doull,Chapter 6 Timbrell, Chapters 4 and 5. Non-polar (lipophilic). Hydrophobic. XENOBIOTIC. Phase I Metabolism. Oxidation. Can accumulate in tissues. Solubility in lipids. INTERMEDIATE METABOLITE.

869 views • 38 slides

Metabolism of Xenobiotics

ENVR/TOXC 442 Fall 2010. Metabolism of Xenobiotics. II. Phase 1 Metabolism Aug 31, 2010 L.M. Ball Rosenau 158 lmball@unc.edu. Phase I reactions. Chemical modification of xenobiotics Introduces or uncovers polar functional groups that provide sites for Phase II metabolism

525 views • 36 slides

Metabolism of Xenobiotics

ENVR/TOXC 442 Fall 2009. Metabolism of Xenobiotics. II. Phase 1 Metabolism Sept 1, 2009 L.M. Ball Rosenau 158 lmball@unc.edu. Phase I reactions. Chemical modification of xenobiotics Introduces or uncovers polar functional groups that provide sites for Phase II metabolism

702 views • 35 slides

Biotransformation Xenobiotic metabolism

841 views • 34 slides

Chapter 1 part 2, slides 35 to the end

Chapter 1 part 2, slides 35 to the end. Antigen binding site. Immunoglobulins (i.e., antibodies). Constant regions Variable regions. What about the TCR effector function ?. Cell plasma membrane.

533 views • 31 slides

Lecture 22 Autoimmunity

Lecture 22 Autoimmunity. Autoimmune Disease. Self tolerance is lost Specific adaptive immune responses mounted against self antigens Inability to eliminate antigen leads to chronic inflammatory process Ehrlich termed this horror autotoxicus.

533 views • 31 slides

Lecture 22 Autoimmunity

Lecture 22 Autoimmunity. Autoimmune Disease. Self tolerance is lost Specific adaptive immune responses mounted against self antigens Inability to eliminate antigen leads to chronic inflammatory process Ehrlich termed this horror autotoxicus.

565 views • 31 slides

Single Nucleotide Polymorphism And Association Studies

Single Nucleotide Polymorphism And Association Studies. Stat 115 Dec 12, 2006. Outline. Definition and motivation SNP distribution and characteristics Allele frequency, LD, population stratification SNP discovery (unknown) and genotyping (known) SNP association studies

515 views • 23 slides

Mutational Spectrum in Egyptian CAH Patients

Mutational Spectrum in Egyptian CAH Patients. AMANY IBRAHIM LECTURER OF PEDIATRICS DEMPU Cairo University, Cairo, Egypt. Introduction.

213 views • 21 slides

Outlining a CONSORT statement

1.04k views • 20 slides

ABSTRACT

Comprehensive overview of K14 sequence variants. Keratin 14 (K14) data. Individual protein record can be accessed via gene symbols or navigation bar. 1. Number of records in the database. K14 mRNA information. K14 protein information. 2. New variants submission form.

357 views • 1 slides

Abstract ID: 3540

Prospective study of EGFR intron 1 CA tandem repeats as predictive factor of benefit from cetuximab and irinotecan

80 views • 1 slides

T. aestivum 5DS

Wheat Grain Hardness: Genetics. XpinA. XpinB. XGsp. T. aestivum 5DS. T. monococcum 5A m. Softness is dominant. Genes at the Ha locus are responsible for the production of Friabilin associated with softness. XNor. Ha.

146 views • 1 slides