Amg 145 - PowerPoint PPT Presentation

Monoclonal Antibodies in CVD: What Does the Future Hold?

Monoclonal Antibodies in CVD: What Does the Future Hold?. Goals. Monoclonal Antibodies: The Basics. Study of Monoclonal Antibodies in CVD. Gain-of-Function vs Loss-of-Function Mutations in PCSK9. The ARIC Study. Mechanism of Action.

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650 views • 25 slides

Robert P. Giugliano, MD, SM, FAHA, FACC TIMI Study Group, Cardiovascular Division

LAPLACE-TIMI 57 Primary Results A Double-blind, Randomized, Placebo-controlled, Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of a Monoclonal Antibody to PCSK9 in Combination with a Statin in Patients with Hypercholesterolemia. Robert P. Giugliano, MD, SM, FAHA, FACC

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273 views • 15 slides

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