'Antisense rna' diaporamas de présentation

Chapter 16 Other RNA Processing Events

Chapter 16 Other RNA Processing Events. Trans-splicing, Editing, RNAi, miRNAs. Trans-splicing section 16.3. First seen in a parasitic protozoa Trypanosomes, protozoan that causes African sleeping sickness

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Gene Action

Gene Action. How does your cell makes very important proteins?. The production (synthesis) of proteins . 3 phases : 1. Transcription 2. mRNA processing 3. Translation. Nuclear membrane. DNA. Transcription. Pre-mRNA. RNA Processing. mRNA. Ribosome. Translation. Protein.

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Introduction to C. elegans and RNA interference

Introduction to C. elegans and RNA interference. Why study model organisms?. The problem:. In order to understand biology, we need to learn about the function of the underlying genes How can we find out what genes do? We need a way to uncover these functions.

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Introduction to C. elegans and RNA interference

Introduction to C. elegans and RNA interference. Why study model organisms?. The problem:. In order to understand biology, we need to learn about the function of the underlying genes How can we find out what genes do? We need a way to uncover these functions.

546 views • 34 slides

Antibiotic discovery - improving the chances.

Antibiotic discovery - improving the chances. Dr Jem Stach. BIO3030-BIO8041. Antibiotics a brief history. Approximately 60 years ago the life expectancy of a child at birth was 45 years. Childhood infection and mortality was very high, and the top 10 causes of death were infection related.

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Antifungal drug discovery.

Antifungal drug discovery. Jem Stach. Fungal Infections. Fungi have emerged as the fourth most common hospital bloodstream infections. Nearly 40% of which prove fatal - particularly significant in patients that are immunocompromised. Resistance to existing classes of drugs is on the increase

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RECOMBINANT DNA TECHNOLOGY

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Biol518

Biol518 . Lecture 2 HTS and Antibiotic Drug Discovery. Modern Drug Discovery. Program Selection Target Selection/ Validation Assay Development HTS Lead Optimization Drug Candidate Selection Clinical Trials Drug Approval Follow-up Monitoring. HTS Workflow.

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13 ?? ????

13 ?? ????. Chapter 18. Regulation at the RNA level. RNA regulation. Degradation rate of mRNA Modification of untranslatable RNA to be translated mRNA translation Binding of antisense RNA to mRNA Riboswitch (part of mRNA that can bind small target molecule) Preferential translation.

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GENE SILENCING

GENE SILENCING. By Dr.S.K.Sarangi Dept.of MB & BT Jnanabharathi Campus Bangalore University Bangalore-560 056. Gene Silencing :. Definition:

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Biotechnology

Biotechnology . Chapter 13. Recombinant DNA . Tools used Restriction enzymes Gel electrophoresis DNA ligase. Restriction enzymes. Cut double stranded DNA into smaller fragments restriction sites Sticky ends Blunt ends . Gel electrophoresis. Separate and purify DNA fragments

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The History of RNAi John Doench

The History of RNAi John Doench. Insight and discovery are functionally separable. The one precedes the other. Insight can happen every day. Discovery does not. Insight takes more intelligence, but it is discovery that is rewarded... Francis Crick. mutate genes at random.

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Conditional systems - principles

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Conditional systems - principles

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