Atm activation - PowerPoint PPT Presentation

The Mre11 complex is required for ATM activation and the G 2 /M checkpoint

The Mre11 complex is required for ATM activation and the G 2 /M checkpoint. Carson, C.T. et al The EMBO J (Vol. 22), 2003. Mre11 complex: Phenotypes. AT: cerebellar degeneration, immune def, IR sensitivity, chromosomal instability, cancer predisposition Mre11: ATLD

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306 views • 19 slides

The effect of chromatin structure on DNA damage signaling

The effect of chromatin structure on DNA damage signaling. Dr. Rebecca Burgess Misteli Lab Cell Biology of Genomes Group National Cancer Institute Bethesda, MD. DNA is compacted into chromatin structures using histone proteins. 11 nm. 30 nm.

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489 views • 15 slides

ATM/p53 Signaling Pathway

ATM/p53 Signaling Pathway. SIGMA-ALDRICH. ATM/p53 Signaling Pathway

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1.76k views • 2 slides

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