Atp dependence - PowerPoint PPT Presentation

Observation: CICR in A7r5 not IP3R or RyR no Passive exchange 2. Characteristics of CICR

Observation: CICR in A7r5 not IP3R or RyR no Passive exchange 2. Characteristics of CICR Ca2+ dependence overlapping stores blocked by MgCl2 ATP dependent 3. Regulation CaM has no effect Inhibition by CaM1234, NCS-1, NCS-1 E120Q, sCaBP1, lCaBP1

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218 views • 11 slides

Observation: CICR in A7r5 not IP 3 R or RyR no Passive exchange 2. Characteristics of CICR

Observation: CICR in A7r5 not IP 3 R or RyR no Passive exchange 2. Characteristics of CICR Ca 2+ dependence blocked by MgCl 2 ATP dependent 3. Regulation CaM has no effect Inhibition by CaM 1234 , NCS-1, NCS-1 E120Q, sCaBP1, lCaBP1

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230 views • 9 slides

ATP dependence

ATP dependence. Ca 2+ dependence. CaM 1234. CaM Pep G Pep H Pep I Pep J. CaM Pep G Pep H Pep I Pep J. CaM Pep G Pep H Pep I Pep J. CaM Pep G Pep H Pep I Pep J. P62 P63 P64 P65 CaM. P62 P63 P64 P65 CaM. 200 M free Ca 2+ CaM:peptide 1:8. 1 mM EGTA

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222 views • 6 slides

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