'Beta lactams' diaporamas de présentation

New Issues in bacteria we thought we knew so well. Meet the new Staphylococcus aureus

New Issues in bacteria we thought we knew so well. Meet the new Staphylococcus aureus. Donna Holton, Infectious Diseases, CHR Oct 23, 2008. HARBOUR BRETON NEWFOUNDLAND. Who am I. ID specialist with training in epidemiology GP who worked in outport NFLD 1981-1983

1.42k views • 131 slides

OVERVIEW OF ANTIMICROBIALS

1.18k views • 97 slides

Chapter 10

Chapter 10. Controlling Microbial Growth in the Body: Antimicrobial Drugs. The History of Antimicrobial Agents. Chemicals that affect physiology in any manner Chemotherapeutic agents Drugs that act against diseases Antimicrobial agents Drugs that treat infections.

871 views • 50 slides

Annual Updated Introduction to Clinically Relevant Microbiology and Antibiotic Use

Annual Updated Introduction to Clinically Relevant Microbiology and Antibiotic Use. Edward L. Goodman, MD, FACP, FIDSA, FSHEA Hospital Epidemiologist Core Faculty Clinical Professor UTSWMS July 7, 2016. Outline . Basic Clinical Bacteriology Antibiotics Categories Pharmacology

434 views • 43 slides

Introduction to Antibacterial Therapy

Introduction to Antibacterial Therapy. Clinically Relevant Microbiology and Pharmacology Edward L. Goodman, MD August 1, 2005. Rationale. Antibiotic use (appropriate or not) leads to microbial resistance Resistance results in increased morbidity, mortality, and cost of healthcare

549 views • 40 slides

Paul M. Tulkens, MD, PhD Cellular and Molecular Pharmacology Unit

Intracellular Pharmacodynamics: a Journey from Cell biology to the Design of New Chemotherapeutic Agents. Paul M. Tulkens, MD, PhD Cellular and Molecular Pharmacology Unit Catholic University of Louvain, Brussels, Belgium & International Society of Antiinfective Pharmacology.

629 views • 40 slides

Introduction to Antibacterial Therapy

Introduction to Antibacterial Therapy. Clinically Relevant Microbiology and Pharmacology Edward L. Goodman, MD July 21, 2003. Rationale. Antibiotic use (appropriate or not) leads to microbial resistance Resistance results in increased morbidity, mortality, and cost of healthcare

432 views • 40 slides

Introduction to Antibacterial Therapy

Introduction to Antibacterial Therapy. Clinically Relevant Microbiology and Pharmacology Edward L. Goodman, MD July 19, 2004. Rationale. Antibiotic use (appropriate or not) leads to microbial resistance Resistance results in increased morbidity, mortality, and cost of healthcare

400 views • 39 slides

Combination Antibiotics

Combination Antibiotics. Mazen Kherallah, MD, FCCP King Faisal Specialist Hospital & Research Center. Mortality Rate Appropriate vs Inappropriate Therapy. Antimicrob agent Chemother 1997 May;41(5):1127-33. In Vitro Results of Combination Therapy.

731 views • 36 slides

Dose optimization as an antimicrobial stewardship strategy

Dose optimization as an antimicrobial stewardship strategy. Jason M. Pogue, PharmD, BCPS, BCIDP Clinical Pharmacist, Infectious Diseases Sinai-Grace Hospital; Detroit Medical Center Clinical Assistant Professor of Medicine Wayne State University School of Medicine. Objectives.

374 views • 34 slides

All About Antibiotics! (in 30 minutes)

All About Antibiotics! (in 30 minutes). George Smulian, MD. Outline. Review of organism classification Antibiotic review by classes Antibiotic mechanisms of action Antibiotic mechanisms of resistance Antibiotic toxicities Questions. Organism classification: Gram stain.

347 views • 34 slides

ANTIBIOTICS

ANTIBIOTICS. SOME GENERAL PRINCIPLES. Antibiotics can be naturally produced, semi-synthetic, or synthetic substances Designed to have as much selective toxicity on the bacteria as possible

483 views • 29 slides

Is Vancomycin Obsolete for Treating Serious Staphylococcal Infections? Part I

Is Vancomycin Obsolete for Treating Serious Staphylococcal Infections? Part I. Edward L. Goodman, MD, FACP, FIDSA, FSHEA August 26, 2009. Outline. Case presentation Are vancomycin failures increasing? Persistence of bacteremia Metastatic foci of infection Longer duration of fever

435 views • 27 slides

Is Vancomycin Obsolete for Treating Serious Staphylococcal Infections? Part I

Is Vancomycin Obsolete for Treating Serious Staphylococcal Infections? Part I. Edward L. Goodman, MD, FACP, FIDSA, FSHEA August 26, 2009. Outline. Case presentation Are vancomycin failures increasing? Persistence of bacteremia Metastatic foci of infection Longer duration of fever

282 views • 27 slides

Drug-induced cutaneous reactions

Drug-induced cutaneous reactions. Ma?gorzata Soko?owska-Wojdy?o, MD, MSc, PhD El?bieta Grubska-Suchanek MD, PhD Department of Dermatology, Venereology and Allergology, Medical University of Gdansk. Drug hypersensitivity.

464 views • 22 slides

Drugs that Inhibit Cell wall synthesis

Drugs that Inhibit Cell wall synthesis. Beta-lactams Penicillin family Cephalosporin family Carbapenems and Monobactams ? -lactamase inhibitors Vancomycin Bacitracin These drugs are bactericidal Failure of the cell wall results in death. Penicillin Family.

411 views • 21 slides

Drugs that Inhibit Cell wall synthesis

Drugs that Inhibit Cell wall synthesis. Beta-lactams Penicillin family Cephalosporin family Carbapenems and Monobactams ? -lactamase inhibitors Vancomycin Bacitracin These drugs are bactericidal Failure of the cell wall results in death. Penicillin Family.

433 views • 21 slides

Plasmid mediated Metallo-Beta-Lactamase (MBL) Plasmid mediated

Plasmid mediated Metallo-Beta-Lactamase (MBL) Plasmid mediated Hydrolyses all beta-lactam (except aztreonam) Inhibited by EDTA Binds zinc (Zn 2+ ) Pseudomonas aeruginosa or Enterobacteriaceae.

238 views • 6 slides

Article Title

Article Title Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Abstract

191 views • 2 slides