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Simvastatin With or Without Ezetimibe in Familial Hypercholesterolemia

Simvastatin With or Without Ezetimibe in Familial Hypercholesterolemia

Simvastatin With or Without Ezetimibe in Familial Hypercholesterolemia. John J.P. Kastelein, MD, PhD * Department of Vascular Medicine Academic Medical Center Amsterdam, The Netherlands. The ENHANCE trial ClinicalTrials.gov number: NCT00552097. *On behalf of all ENHANCE investigators.

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542 views • 26 slides
TNT: New data on intensive lipid lowering in stable CHD patients

TNT: New data on intensive lipid lowering in stable CHD patients

TNT: New data on intensive lipid lowering in stable CHD patients. Hypothesis: Lowering LDL-C levels to well below 100 mg/dL could yield an incremental clinical benefit Participants: 10,001 patients with stable CHD and LDL-C 130-250 mg/dL Treatments: Atorvastatin 10 mg and 80 mg

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275 views • 16 slides
HDL-c levels and non-ABCA1-specific cholesterol efflux capacity after CETP-inhibition or placebo

HDL-c levels and non-ABCA1-specific cholesterol efflux capacity after CETP-inhibition or placebo

HDL-c levels and non-ABCA1-specific cholesterol efflux capacity after CETP-inhibition or placebo. 70. 60. placebo. 30. dalcetrapib. 50. HDL-cholesterol (mg/dL). 20. % change from baseline in non-ABCA1-specific cholesterol efflux. 40. placebo. dalcetrapib. 30. 10. 20. 0. 0. 4. 8.

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147 views • 1 slides
LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients

LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients

LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients. 25. 2 null alleles. 20. 1 null allele, 1 defective allele. 2 defective alleles. 15. 10. LDL-c levels (mmol/L). 5. 0. Before lipid-lowering therapy. After lipid-lowering therapy.

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88 views • 1 slides

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