'C1 inh' diaporamas de présentation

ANGIOEDEMA, LARYNGEAL EDEMA DIAGNOSIS AND MANAGEMENT

ANGIOEDEMA, LARYNGEAL EDEMA DIAGNOSIS AND MANAGEMENT. Henriette Farkas Semmelweis University 3 rd Department of Internal Medicine Budapest, Hungary. farkash@kut.sote.hu. UPPER AIRWAY OBSTRUCTION (UAO) AETIOLOGY. MECHANICAL CAUSES Foreign body aspiration Infections Laryngeal edema

650 views • 49 slides

Angioedema 11/12/2010

Angioedema 11/12/2010. BY: MOHAMMED ALSAIDAN. Angioedema. Abrupt and short-lived swelling of the skin, mucous membranes, or both including the upper respiratory and intestinal epithelial linings The swelling is nonpitting, erythematous or skin-colored Areas where the skin is lax

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Hereditary A ngioedema

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656 views • 29 slides

Immune Response and Hormonal Alterations in C1-inhibitor Deficiency

Immune Response and Hormonal Alterations in C1-inhibitor Deficiency. Vojtech Thon. University Centre for Primary Immunodeficiencies Department of Clinical Immunology and Allergology St. Anne University Hospital, Masaryk University Brno, Czech Republic. H ereditary angioedema.

520 views • 28 slides

Immune Response and Hormonal Alterations in C1-inhibitor Deficiency

Immune Response and Hormonal Alterations in C1-inhibitor Deficiency. Vojtech Thon. University Centre for Primary Immunodeficiencies Department of Clinical Immunology and Allergology St. Anne University Hospital, Masaryk University Brno, Czech Republic. H ereditary angioedema.

303 views • 28 slides

WAO Global Hereditary Angioedema (HAE) Practice Parameter

WAO Global Hereditary Angioedema (HAE) Practice Parameter. Timothy J. Craig, DO Professor of Medicine and Pediatrics Distinguished Educator Chief, Allergy, Asthma, and Immunology Program Director

485 views • 27 slides

Hereditary Angioedema: Pathogenesis of Attacks

Hereditary Angioedema: Pathogenesis of Attacks. Michael M. Frank, MD Samuel Katz Professor of Pediatrics, Medicine and Immunology Duke University Medical Center. Conflict of interest. 5 companies (Lev, CSL Behring, Jerini, Pharming, Dyax) have completed trials of therapy for HAE.

633 views • 27 slides

Hereditary Angioedema

Hereditary Angioedema. Initially described by Osler in 1888, HAE is an autosomal dominant disease caused by a deficiency in functional C1 inhibitor. More than 150 point mutations of SERPING1 (the gene encoding for C1-INH) have been described Prevalence 1:50000 (rare disease).

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Factor B-/- mice

C1-Inh. C3 convertase inhibitors (Crry-Ig, sCR1, rVCP). Factor B-/- mice. mAb1379. C5a antagonists. Anti-C5aR (CD88) Abs. Anti-C5 Abs.

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Successful Treatment of Acquired Angioedema Using B-lymphocyte Depletion Therapy

Successful Treatment of Acquired Angioedema Using B-lymphocyte Depletion Therapy Chang Na, MD, David Podell, MD, Christopher Randolph, David Dreyfus, Denise Kearney. Yale Primary Care Program, Waterbury, CT 1,2 , Allergy, Asthma & Immunology, Waterbury, CT 3,4,5.

107 views • 1 slides