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Chronic Liver Disease. Chronic Liver Disease. Outline: Definition Epidemiology Clinical Presentation History/PE Labs Radiographs Management of complications Ascites (including HRS, SBP) HE Variceal hemorrhage HCC. CLD- Pathophysiology.
Chronic Liver Disease. For final year medical students 2014 Dr Rosalind Pool GPST1. Objectives. List signs and symptoms of CLD List causes of CLD Understand LFTs How to investigate CLD Management of CLD Apply knowledge to a case study. Why might you suspect liver failure?.
Chronic liver disease. Waleed Al-hamoudi Gastroentrology and hepatology unit. Case.
Chronic Liver Disease . Simon Lynes. Definition. Progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. Aetiology. Vascular – Budd Chiari Infectious – viral hepatitis B and C T Autoimmune – PBC/PSC, autoimmune hepatitis
Chronic liver disease. Definition. Pathologic Liver biopsy showing features of chronic inflammation or cirrhosis (Metavir, Knodell ’ s Scoring … ) Etiology Clinical Features of chronic liver stigmata, complications including portal hypertension. Etiology. Infection Alcohol Autoimmune
Chronic Liver Disease. Decompensated liver disease : Severe liver disease leading to encephalopathy, coagulopathy and jaundice Cirrhosis: Histological diagnosis . Functions of the liver Synthesis ( gluconeogenesis , glycogenesis , protein, cholesterol, coag factors, bile)
Glucose homeostasis; glycogenolysis & gluconeogenesis. Catabolism of hormones and other serum proteins. Chronic Liver Disease. Synthesis: Albumin Coagulation factors. Katharine Brown. Storage: Glycogen Iron Cu, Iron, vitamins. Bile excretion. Objectives.
Chronic Liver Disease. Tim Badcock FY1 Colorectal surgery 21/10/13. Plan. Introduction to the liver Definition Clinical Scenario Presentation Aetiology Complications Investigations Management Prognosis. Introduction to the liver. 5 Functional domains 4 lobes 3 vascular
Cooperation Bilharz-Beaujon Cairo - March 16-18, 2008. PVT In Patients With Chronic Liver Disease. Dominique-Charles Valla Hôpital Beaujon, APHP, Université Paris-7, Inserm CR3B. PVT in Patients with Cirrhosis. Epidemiology Manifestations Causal factors Therapy.