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CELLS& ORGANS OF IMMUNE MECHANISM.

CELLS& ORGANS OF IMMUNE MECHANISM.

CELLS& ORGANS OF IMMUNE MECHANISM. Origin & structure. IMMUNE CELLS. Fetal liver -------------yolk cells Blood cell precursors. Stem cells reside in bone marrow. Erythroid, myeloid& lymphoid series. Lymphocyte populations. T-Lymphocytes (cytotoxic &helper T-cells).

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650 views • 42 slides
MOLECULES INVOLVED IN CELLULAR INTERACTION

MOLECULES INVOLVED IN CELLULAR INTERACTION

MOLECULES INVOLVED IN CELLULAR INTERACTION. CYTOKINES. Low molecular Soluble protein messengers Common subunit receptors (heterodimers) Lymphocyte derived ? lymphokine Monocyte derived ? Monokine Involved ?n leukocyte interaction ? Interleukines.

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374 views • 30 slides
Chapter 15 Immunological Tolerance

Chapter 15 Immunological Tolerance

Chapter 15 Immunological Tolerance. Outline. 1.Concept Immunological Tolerance: These antigen specific T cells and B cells can not be activated to induce immune response under stimulation of Ag. This phenomenon is called immunological tolerance. Tolerogen: antigens that induce tolerance.

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311 views • 29 slides
Tolerance, Autoimmunity, Immunodeficiences

Tolerance, Autoimmunity, Immunodeficiences

Tolerance, Autoimmunity, Immunodeficiences. Tolerance. Tolerance is broadly defined as a state of unresponsiveness to an antigen, be it self or foreign Antigen-specific cell receives signals that either activate OR inactivate the cell

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472 views • 28 slides
Immunogen, antigen, epitope, hapten

Immunogen, antigen, epitope, hapten

Immunogen, antigen, epitope, hapten. Immunogen: a stimulus that produces a humoral or cell-mediated immune response Antigen: any substance that binds specifically to an antibody or a T-cell receptor. Immunogen, antigen, epitope, hapten.

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927 views • 28 slides
Computational Immunology An Introduction

Computational Immunology An Introduction

Computational Immunology An Introduction. Rose Hoberman BioLM Seminar April 2003. Overview. Brief intro to adaptive immune system B and T cells Achieving specificity Antibodies, TCR, MHC molecules Maintaining tolerance to self Clonal selection/deletion in the thymus Paper:

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1.04k views • 25 slides
Computational Immunology An Introduction

Computational Immunology An Introduction

Computational Immunology An Introduction. Rose Hoberman BioLM Seminar April 2003. Overview. Brief intro to adaptive immune system B and T cells Achieving specificity Antibodies, TCR, MHC molecules Maintaining tolerance to self Clonal selection/deletion in the thymus Paper:

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350 views • 25 slides
Innate vs. Adaptive Immunity

Innate vs. Adaptive Immunity

Primitive (found in all multicellular organisms) Directed towards types of molecules Effectors are broadly reactive Response is immediate No anamnestic responses Effectors: epithelial cells, phagocytes, endothelial cells, fibroblasts. Only in vertebrates Directed towards specific epitopes

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914 views • 22 slides
Immune System Vocabulary

Immune System Vocabulary

Immune System Vocabulary. Part 2. a surface protein on a pathogen that causes antibodies to be generated by white blood cells. When T cell receptors and the antibodies produced by B cells recognize and bind to antigens, a specific immune response is initiated. . Antigen.

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325 views • 20 slides

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