Compound selection - PowerPoint PPT Presentation

Pre-processing HCS data using Non-negative Matrix Factorization

Pre-processing HCS data using Non-negative Matrix Factorization. S. Stanley Young National Institute of Statistical Sciences MBSW, Muncie 19May2009. WH. Contention: PCA fails for mixtures. NMF separates mixtures. Y 1. +. Y 2. =. WH. NMF. Y. Key Idea. Outline. Basics of HCS

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614 views • 35 slides

Imaging in Oncology Clinical Trials

Imaging in Oncology Clinical Trials. Susan Galbraith Clinical Discovery Bristol-Myers Squibb. What can we see?. Microvasculature Blood volume - MRI, PET Vessel permeability - MRI Blood flow - PET, MRI, SPECT Hypoxia - MRI, PET VEGF - PET. What can we see?.

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764 views • 34 slides

Drug Design / drug discovery

Drug Design / drug discovery. Jerome Baudry Assistant Professor BCMB UT/ORNL Center for Molecular Biophysics. 2 previous incarnations: Research faculty at UIUC Research scientist at Transtech Pharma, Inc. . Drug Design / drug discovery. What’s a drug?

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1.16k views • 26 slides

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