'Covariate information' diaporamas de présentation

Statistical issues in QTL mapping in mice

Statistical issues in QTL mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Outline. Overview of QTL mapping The X chromosome Mapping multiple QTLs Recombinant inbred lines Heterogeneous stock and 8-way RILs.

760 views • 61 slides

Gene mapping in mice

Gene mapping in mice. Karl W Broman Department of Biostatistics Johns Hopkins University http://www.biostat.jhsph.edu/~kbroman. Goal. Identify genes that contribute to common human diseases. Inbred mice. Advantages of the mouse. Small and cheap Inbred lines Large, controlled crosses

656 views • 45 slides

The DIMACS Working Group on Disease and Adverse Event Surveillance

The DIMACS Working Group on Disease and Adverse Event Surveillance. Henry Rolka and David Madigan. Background. WG Objective: Bring together researchers in adverse event monitoring and disease surveillance Part of a 5-year special focus on computational and mathematical epidemiology

482 views • 34 slides

QTL mapping in mice, completed.

QTL mapping in mice, completed. Lecture 12, Statistics 246 March 2, 2004. REVIEW. n backcross mice; M markers in all, with at most a handful expected to be near QTL x ij = genotype (0/1) of mouse i at marker j y i = phenotype (trait value) of mouse i

464 views • 32 slides

SAMSI Tutorial on Dynamic Treatment Regimes by Anastasios Tsiatis

SAMSI Tutorial on Dynamic Treatment Regimes by Anastasios Tsiatis. Dr. Gong Tang Wentao Feng Sachiko Miyahara. Introduction. Goal of Physicians : To give treatment to patients over time that will result in as favorable a clinical outcome as possible. Introduction (Cont.).

257 views • 22 slides

Rerandomization in Randomized Experiments

272 views • 12 slides