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Determine dna sequence - PowerPoint PPT Presentation

Microbial genomics

Microbial genomics. Genomics: study of entire genomes Logical next step after genetics: study of genes. Genomics: 1) “Structural genomics” * Determine and annotate DNA sequence of entire genome * Determining crystal structure for all predicted proteins 2) Functional genomics

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940 views • 24 slides

Unit 9 Biotechnology and Genomics

Unit 9 Biotechnology and Genomics. I. How can we use DNA to help humans? A. DNA Fingerprinting 1. Each individual (except clones and identical twins) has a unique DNA sequence . This sequence can be used to produce a DNA fingerprint , a unique band pattern of DNA fragments.

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326 views • 20 slides

Sickle-cell anemia

Sickle-cell anemia. Caused by single bp substitution in b -globin gene. Determine b -globin genotype by RFLP analysis. Other methods to diagnose genotypes. Allele-specific Oligonucleotides (ASOs): Make two oligonucleotide probes: (a) Normal sequence (b) Sequence of mutant allele

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448 views • 10 slides

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Determine dna sequence - PowerPoint PPT Presentation

Microbial genomics

Unit 9 Biotechnology and Genomics

Sickle-cell anemia