'Draft sequence' diaporamas de présentation

Whole Genome Alignment

Whole Genome Alignment. Adam M Phillippy amp@cs.umd.edu. CCGGTAGGCTATTAAACGGGGTGAGGAGCGTTGGCATAGCA. CCGGTAGGCTATTAAACGGGGTGAGGAGCGTTGGCATAGCA. Goal of WGA. For two genomes, A and B , find a mapping from each position in A to its corresponding position in B. 41 bp genome.

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Genome sizes (sample)

Genome sizes (sample). Some genomics history. 1995: first bacterial genome, Haemophilus influenza , 1.8 Mbp, sequenced at TIGR first use of whole-genome shotgun for a bacterium Fleischmann et al. 1995 became most-cited paper of the year (>3000 citations)

670 views • 50 slides

Whole Genome Alignment

Whole Genome Alignment. MUMmer and Alignment October 2 nd , 2007 Adam M Phillippy amp@cs.umd.edu. CCGGTAGGCTATTAAACGGGGTGAGGAGCGTTGGCATAGCA. CCGGTAGGCTATTAAACGGGGTGAGGAGCGTTGGCATAGCA. Goal of WGA.

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CUGI Pilot Sequencing/Assembly Projects

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Annotation of Mouse Draft Sequence by Comparative Analysis to Human Sequence

Annotation of Mouse Draft Sequence by Comparative Analysis to Human Sequence. M. Bucan, T. Wiltshire, A. Lengeling, L. Tarantino, S. Kanes CNB, University of Pennsylvania J. Crabtree, J. Schug, C. Overton, C. Stoeckert CBIL, University of Pennsylvania J. Lehoczky, K. Dewar, B. Birren and the

185 views • 18 slides