Epigenetic therapy - PowerPoint PPT Presentation

Epigenetic Therapy

Epigenetic Therapy. Jean-Pierre Issa University of Texas at MD Anderson Cancer Center. Epigenetics. Clonal and irreversible changes in gene expression that cannot be attributed to changes in DNA sequence

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Progress of epigenetic therapy

Progress of epigenetic therapy. Melissa Sylvester. intro. Moss and Wallrath demonstrated that in some cases reversal of cancer is possible, because of the connection between human disease and epigenetic silencing.

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Azad, N. et al. ( 2013) The future of epigenetic therapy in solid tumours—lessons from the past

Table 1 Selected trials of epigenetic therapy. Azad, N. et al. ( 2013) The future of epigenetic therapy in solid tumours—lessons from the past Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2013.42.

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138 views • 1 slides

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