'Erk' diaporamas de présentation

Content Biological pathways and crosstalk Simulation model development

Lecture 2: Overview of Computer Simulation of Biological Pathways and Network Crosstalk Y.Z. Chen Department of Pharmacy National University of Singapore Tel: 65-6616-6877; Email: phacyz@nus.edu.sg ; Web: http://bidd.nus.edu.sg. Content Biological pathways and crosstalk

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Visualizing Angiogenesis

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Abstract Background

P-S6 Response to LPS Stimulation. 0 min. 4 min. P-p38 Alexa 488. P-S6 Pac Blue. P-S6 Pac Blue. Ly294002. P-SAPK PE. UO126. 15 min. 60 min. 10 min. 4 min. P-ERK Alexa 647. +UO126. +LPS. +UO126. +LPS. P-S6 Pac Blue. P-S6 Pac Blue. + LPS. Control. P-S6 Pacific Blue.

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Growth factors

Growth factors. nutrients. translation. Ad VA RNAs. PKR. p70S6K. Ad E4-ORF4. PIP3. eIF-4E. EIF2 a. PTEN. PDK1. RHEB. mTOR. 4E-BP1. PERK. TSC1/2. PI3K. ER stress. Ca 2+. AMPK. Cyt c. Ad E4-ORF1. Apoptosis/cell death. AKT (PKB). Ras. Caspase cascade. Raf. GSK3. Bax/Bak.

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ERK

A. p-JNK. p-JNK. JNK. JNK. *. p-JNK/JNK Related density (% of LPS group). *. p-ERK. P-JNK/JNK Related densityu (% of LPS group). p-ERK. *. *. *. ERK. *. ERK. *. *. *. p-p38. p-p38. - + + + + + +

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Abstract Background

P-S6 Response to LPS Stimulation. 0 min. 4 min. P-p38 Alexa 488. P-S6 Pac Blue. P-S6 Pac Blue. Ly294002. P-SAPK PE. UO126. 15 min. 60 min. 10 min. 4 min. P-ERK Alexa 647. +UO126. +LPS. +UO126. +LPS. P-S6 Pac Blue. P-S6 Pac Blue. + LPS. Control. P-S6 Pacific Blue.

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Erk Signaling Pathway

Erk Signaling Pathway: http://www.creative-diagnostics.com/Erk-Signaling-Pathway.htm

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