Esomeprazole - PowerPoint PPT Presentation

Upper GI Bleeding

Upper GI Bleeding. Dr M. Ghanem. Definition. Refers to GI bleeding from a source proximal to the Ligament of Treitz. Presentation. Hematemesis Coffee-ground vomiting Melena Hematochezia. Causes. Initial Evaluation. ABC’s History: Bleeding Manifestations PMHx Medications? P/E:

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Andersson, T, et al. Clin Pharmacokinet 2001;40:411-26. Hassan-Alin, M, et al. Eur J Clin Pharmacol 2000;56:665-70.

Population Pharmacokinetic Modelling of Esomeprazole Nonlinearity Joseph F Standing (1), Marie Sandström (2), Tommy Andersson (2), Kerstin Röhss (2), Mats O Karlsson (1) (1) Department of Pharmaceutical Biosciences, Uppsala University, Sweden; (2) AstraZeneca Ltd., Sweden. Background.

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