'Exons' diaporamas de présentation

Alternative splicing: A playground of evolution

Alternative splicing: A playground of evolution. Mikhail Gelfand Research and Training Center for Bioinformatics Institute for Information Transmission Problems RAS, Moscow, Russia RECOMB, 20 May 2008. % of alternatively splic ed human and mouse genes , by year of publication. 100%.

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Gene expression

Gene expression. Have you ever wondered how a frog grows?. http://www.teara.govt.nz/en/frogs. Native male frogs sit on the eggs and the young froglets hatch almost fully formed. http://www.erodent.co.uk/GardenPond/PondPhotos/Tadpole3w.jpg. Why are their parts where they are?.

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Alternative splicing: A playground of evolution

Alternative splicing: A playground of evolution. Mikhail Gelfand Research and Training Center for Bioinformatics Institute for Information Transmission Problems RAS, Moscow, Russia October 2008. % of alternatively splic ed human and mouse genes by year of publication.

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Alternative splicing: A playground of evolution

Alternative splicing: A playground of evolution. Mikhail Gelfand Research and Training Center for Bioinformatics Institute for Information Transmission Problems. Alternative splicing of human (and mouse) genes. Evolution of alternative exon-intron structure human-mouse

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Gene Structure and Identification

Gene Structure and Identification. Eukaryotic Genes and Genomes Gene Finding. Previous reading: 1.3, 9.1-9.6 Reading: 10.2, 10.4, 10.6-8. BIO520 Bioinformatics Jim Lund. ~10% highly repetitive (300 Mbp) NOT GENES ~25% moderate repetitive (750 Mbp) Some genes

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Figure Additional 1

Additional figures for Differential expression of 24,426 human alternative splicing events and predicted cis-regulation in 48 tissues and cell lines John C. Castle, Chaolin Zhang, Jyoti K. Shah, Amit V. Kulkarni, Thomas A. Cooper, Jason M. Johnson.

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Alternative splicing: A playground of evolution

Alternative splicing: A playground of evolution. Mikhail Gelfand Research and Training Center for Bioinformatics Institute for Information Transmission Problems RAS, Moscow, Russia October 2006. % of alternatively splic ed human and mouse genes by year of publication.

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Chap. 1 Molecular and Biological Chemistry

Chap. 1 Molecular and Biological Chemistry. BIOINFORMATICS ? BT(Bio Technology) + IT(Information Technology). Evolution. Developmental Biology. Transcriptomics. Phylogenetics. Bioinformatics. Genetics. System Biology. Proteomics. Molecular Biology. Structure o f DNA. Nucleotides.

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Analysis of the RNAseq Genome Annotation Assessment Project

Analysis of the RNAseq Genome Annotation Assessment Project. by Subhajyoti De. ?. ?. ?. The RNAseq Genome Annotation Assessment Project. The RGASP aims to assess the current progress of automatic gene building using RNAseq as its primary dataset.

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Evidence for exon-mediated domain shuffling in the formation of complex eukaryotic genes

Evidence for exon-mediated domain shuffling in the formation of complex eukaryotic genes. Albert DG de Roos, Syncyte BioIntelligence albert.de.roos@syncyte.com December 2008. Introduction.

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SPIDA Substitution Periodicity Index and Domain Analysis

SPIDA Substitution Periodicity Index and Domain Analysis. Combining comparative sequence analysis with EST alignment to identify coding regions Damian Keefe Birney Group EBI. SPIDA - Motivation. Improve UTR annotation Make use of the ever expanding EST resource - good UTR source

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tRNA

tRNA. tRNA. Transfer RNA (tRNA) is a small molecule, existing as a single-strand that is folded into a clover-leaf shape. tRNA. The role of tRNA is to bring the amino acids to a ribosome where protein synthesis is taking place. (more on this later).

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Comparative Genomics Methods for Alternative Splicing of Eukaryotic Genes

Comparative Genomics Methods for Alternative Splicing of Eukaryotic Genes. Liliana Florea Department of Computer Science Department of Biochemistry GWU florea@gwu.edu 202-994-1057. Jan 24th, 2007. Alternative Splicing.

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Exons and Introns

Exons and Introns. -RNA transcript, while in the nucleus, is composed of exons, sequences of nucleotides that carry useful information for protein synthesis, and introns, sequences that do not. Exons and Introns. -Before leaving the nucleus, introns are removed and exons are spliced together.

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