'Factor ix' diaporamas de présentation

Hemophilia & von willibrand disease

Hemophilia & von willibrand disease. Dr.Padmashini. objectives. History Introduction Definition Clinical Features Diagnosis Available treatment modalities. Best known of the hereditary bleeding disorders. First coined by Schonlein in 1820s.

1.28k views • 59 slides

IB Genetics Topic 4:

IB Genetics Topic 4:. Genetic Engineering. Topics in Genetic Engineering. Polymerase Chain Reaction (PCR) Gel electrophoresis DNA profiling The genome project Gene transfer Genetic modification in plants and animals Cloning. We will be brief!.

742 views • 56 slides

12/1/03 11:01 PM

12/1/03 11:01 PM. SELEX Have a random 40-mer synthesized, between 2 arbitrary 20-mers (PCR sites) 4 40 = 10 24 Practical limit = 10 15 = ~ 2 nmoles = ~ 50 ug DNA 10 15 is a large number. Very large (e.g., 500,000 times as many as all the unique 40-mers in the human genome.

531 views • 44 slides

Nucleic acid aptamers

Nucleic acid aptamers Aptamers: molecules that bind other molecules with good affinity and specificity Usually these are proteins . . . . But they can also be RNA or DNA.

807 views • 43 slides

Hemophilia B

1.88k views • 41 slides

NORMAL HAEMOSTASIS:

NORMAL HAEMOSTASIS:. It is a complex process depending on interaction between vessel wall, platelets and coagulation factors. NORMAL HAEMOSTASIS. Vessel wall.

787 views • 35 slides

Coagulation

Coagulation. Janell Wilcox, PA-C. Hemostasis. Definition: clotting of the blood Phases Formation of the platelet plug Coagulation cascade Termination of clotting by antithrombotic control mechanisms Removal of the clot by fibrolysis. Clotting diagram.

837 views • 35 slides

Hemostasis and Blood Coagulation Events in Hemostasis

Hemostasis and Blood Coagulation Events in Hemostasis The term hemostasis means prevention of blood loss. Whenever a vessel is severed or ruptured,

804 views • 33 slides

Sex linked genes

581 views • 33 slides

Coagulation factor disorders

Coagulation factor disorders. Dr. Maji Jose. Coagulation factor disorders. Inherited bleeding disorders Hemophilia A and B vonWillebrands disease Other factor deficiencies Acquired bleeding disorders Liver disease Vitamin K deficiency/ warfarin overdose DIC. HAEMOPHILIA.

1.1k views • 32 slides

Objectives

Eukaryotic Gene Regulation April 23, 2014 Richard D. Howells, PhD MSB E-643 howells@njms.rutgers.edu. Objectives. During this presentation you may Catch another 40 winks, or Understand key concepts regarding regulation of gene expression in eukaryotes. Eukaryotic RNA Polymerases. 3.

459 views • 31 slides

The hemophilias A and B

The hemophilias A and B. X-linked hereditary blood clotting disorders due to deficiency of factor VIII (hemophilia A) or factor IX (hemophilia B) Identical clinical manifestations, screening tests abnormalities and sex-linked genetic transmission. Epidemiology. The incidence rate:

658 views • 29 slides

Disclosure Statement of Financial Interest

Pegnivacogin (RB006), a Direct Factor IXa Inhibitor, Results in Consistent and Near Complete Inhibition of Factor IX Activity in Patients with Acute Coronary Syndromes: A Prospective RADAR Pharmacokinetic and Pharmacodynamic Substudy.

741 views • 28 slides

PRENATAL DIAGNOSIS OF HAEMOPHILA

PRENATAL DIAGNOSIS OF HAEMOPHILA. Huong Le Senior Hospital Scientist Department of Molecular & Clinical Genetics Royal Prince Alfred Hospital Sydney , Australia. OUTLINE. Introduction Haemophilia A (Factor VIII) Haemophilia B (Factor IX) The related genes Genetic testing. INTRODUCTION.

610 views • 28 slides

HAEMOSTASIS AND THROMBOSIS

HAEMOSTASIS AND THROMBOSIS. The integrity of the circulation is maintained by blood flowing through intact vessels lined by endothelial cells. Injury to the vessel wall exposes collagen and together with tissue injury sets in motion a series of events leading to haemostasis. HAEMOSTASIS

461 views • 27 slides

Coagulation Disorders

Coagulation Disorders. FACTOR VIII DEFICIENCY HEMOPHILIA A. Factor VIII: Regulates the activation of factor X by proteases. Synthesized in liver, complexed to vWF. On the X chromosome. HEMOPHILIA A. Female carriers have sufficient factor VIII.

652 views • 27 slides

Advances in gene therapy for phenylketonuria (PKU)

Advances in gene therapy for phenylketonuria (PKU). Cary O. Harding, MD Department of Molecular & Medical Genetics. Disclosures. BioMarin Corporation Funds for participation in clinical trials Sapropterin dihydrochloride rAvPAL-PEG National PKU Alliance Funds for PKU gene therapy research.

577 views • 22 slides

Bleeding and coagulation disorders

Bleeding and coagulation disorders. Bleeding and coagulation disorders. any bleeding or coagulation defect may be : Platelet defects; Clotting factor defects which may be due to: Decreased production . Presence of antagonism e.g. heparin.

826 views • 19 slides

308 views • 16 slides

360 views • 10 slides