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Introduction to Steady State Metabolic Modeling

Introduction to Steady State Metabolic Modeling

Introduction to Steady State Metabolic Modeling. Concepts Flux Balance Analysis Applications Predicting knockout phenotypes Quantitative Flux Prediction Lab Practical Flux Balance Analysis of E. coli central metabolism Predicting knockout phenotypes

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932 views • 50 slides
October 20, 2010 Daniela Calvetti

October 20, 2010 Daniela Calvetti

Accounting for variability and uncertainty in a brain metabolism model via a probabilistic framework. October 20, 2010 Daniela Calvetti. Brain is a complex biochemical device. Neurons and astrocytes are linked via a complex metabolic coupling

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487 views • 38 slides
Ems vs. OptKnock vs. OptFlux

Ems vs. OptKnock vs. OptFlux

Ems vs. OptKnock vs. OptFlux. 10 ? ???. Ems. Ems ????????????? ? ??????????. Ems ??? MPA. ????????????????? Ems ???. ????. ???? ?? Ems. ??? ??????????. OptKnock. ?genome-scale models of metabolism.

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595 views • 22 slides
Gene regulation and metabolic flux reorganization in aerobic/anaerobic switch of E. coli

Gene regulation and metabolic flux reorganization in aerobic/anaerobic switch of E. coli

Gene regulation and metabolic flux reorganization in aerobic/anaerobic switch of E. coli. Chao WANG July 19, 2006. E. coli is a prokaryote model organism with relatively complete knowledge on both transcriptional regulation (TR) and metabolism.

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316 views • 22 slides
Metabolic Modeling - Why?

Metabolic Modeling - Why?

Metabolic Modeling - Why?. Models - why? Building models of a system helps us improve our understanding. It is also a way of checking our understanding, as comparison of a model with reality is the way to prove whether the model works. Models of metabolic pathways - why?

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258 views • 11 slides
Bioinformatics Laboratory (AMC) Medical bioinformatics & e-Bioscience Antoine van Kampen

Bioinformatics Laboratory (AMC) Medical bioinformatics & e-Bioscience Antoine van Kampen

Bioinformatics Laboratory (AMC) Medical bioinformatics & e-Bioscience Antoine van Kampen. Scope: Research, Education, AMC Support Focus areas: Systems Genomics (biological pathways), e-Science Microarrays, Next Generation Sequencing, Metabolomics (LC-MS), Immunology

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192 views • 1 slides

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