RENAL DISEASE: CHRONIC RENAL FAILURE Pathophysiology of Disease: Chapter 16 (394-398). Jack DeRuiter, PhD Department of Pharmacal Sciences April, 2000. ETIOLOGY (page 394). Diabetes mellitus (28%) Hypertension (25%) Glomerulonephritis (21%) Polycystic Kidney Diease (4%)By roary-holloway
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Structural Abnormalities. Deletions. Translocations. Inversions. Duplications. Deletions. Small or large. Mutation in one or many genes. Homozygosity or heterozygosity for each. Consequences for gene function. Deletions. Loss of chromosomal material Large-scale deletions are lethal
Erythrocyte Abnormalities. Clinical Pathology, Ms. Canga. Erythrocyte Morphology. Different species have different _________ RBCs with varying degrees of ___________________________ . Dogs have _____________ RBCs (~________ µm in diameter) Cats, horses, cows, sheep, goats (3-4 µm)
Metabolic Abnormalities. Asha Bale, MD Surgical Fundamentals Lecture #6. Overview. Symptoms, Etiology, Treatment Sodium Potassium Magnesium Calcium Glucose abnormalities Arrhythmias. Hyponatremia Na<136. Most Common causes are Iatrogenic or SIADH Sx: CNS (increased ICP)
Metabolic Abnormalities. Surgical Fundamentals Lecture Asha Bale, MD 8/06/10. Overview. Symptoms, Etiology, Treatment Sodium Potassium Magnesium Calcium Glucose abnormalities Arrhythmias. Hyponatremia Na<136. Most Common causes are Iatrogenic or SIADH Sx: CNS (increased ICP)
REPOLARIZATION ABNORMALITIES. INTRODUCTION- T WAVE & ST SEGMENT ABNORMALITIES.
CHROMOSOMAL ABNORMALITIES. By Dr Samina Anjum. CAUSES OF BIRTH DEFECTS & SPONTANEOUS ABORTIONS ARE Chromosomal abnormalities Genetic factors. INCIDENCE FOR MAJOR CHROMOSOMAL ABNORMALITIES.
Chromosomal Abnormalities. Down Syndrome. Jacob’s Syndrome. WARNING : This image may be disturbing to some individuals. Pataos Syndrome. Turner’s Syndrome. Klinefelter’s Syndrome. Cri Du Chat. Edward’s Syndrome. Treacher Collins syndrome and a cleft palate.
Electrolyte Abnormalities. 3 July 2008 Justin A. Glass, MD Emory Family Medicine. Goals. Review of common electrolyte abnormalities Normal ranges Clinical manifestations of hypo- or hyper- states Causes Treatment options. Goals. What will spend time on today… Sodium Potassium
Chromosomal Abnormalities. Jane Yoo HST.180 January 27, 2004. Genetic Disorders. Cytogenetic Disorders Gross chromosomal abnormalities Single Gene Disorders Classical (Mendelian) inheritance Non-classical inheritance Mitochondrial genes Trinucleotide repeats