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Multiplex Ligation-dependent Probe Amplification (MLPA )

Multiplex Ligation-dependent Probe Amplification (MLPA ). For large deletion and deletion in unpredicted sites and duplication we can use MLPA In detection of aneupolidy e.g. trisomy 13,18 and 21 and monosomy turner. In this case probes are designed against STRs.

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Multiplex Ligation-dependent Probe Amplification (MLPA )