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QTL Mapping in Diversity Outbred Mice

QTL Mapping in Diversity Outbred Mice. Daniel M. Gatti, Ph.D Berlin, Germany May 2014. Outline. Introduction Genotyping Diversity Outbred Mice Quantitative Trait Locus mapping in DO mice. Motivation for producing the DO. Known founders to perform linkage mapping

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469 views • 44 slides

QTL mapping

QTL mapping. Simple Mendelian traits are caused by a single locus, and come in the ‘ all-or-none ’ flavor. A Quantitative Trait is one in which many loci contribute. The phenotype can therefore vary in a ‘ quantitative ’ manner. Ades 2008, NHGRI. Modified from Mike White slides, 2010.

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858 views • 23 slides

Selection for Scrapie resistance based on PrP polymorphism

Selection for Scrapie resistance based on PrP polymorphism. A simulation study. Vitezica Zulma, Palhière Isabelle, Manfredi Eduardo, Elsen Jean Michel SAGA-INRA, Toulouse, France. Selection for Scrapie resistance…. Importance of Scrapie Simulation description

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367 views • 19 slides

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