Global fdr - PowerPoint PPT Presentation

Global FDR analysis

Global FDR analysis. The False Discovery Rate gives us a value for the proportion of our discoveries that are false discoveries. Multiple Test Hypothesis. Step 1: Experiment  data table. Step 4: Shuffle Patient I.D.’s. Step 5: Repeat Step 2. Step 2:

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Limitations of Global FDR

Limitations of Global FDR. Less likely to be false positive. More likely to be false positive. Global FDR rejection region. threshold. 0. 1. Single hypothesis testing P -values. Global FDR method cannot associate the corrected significance with each hypothesis testing

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