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Haplotype construction - PowerPoint PPT Presentation


G enotyping & Haplotyping

G enotyping & Haplotyping

G enotyping & Haplotyping. Genotyping. Analysis of DNA-sequence variation Human DNA sequence is 99.9% identical between individuals →3000 000 varying nucleotides Polymorphism: normal variation between individuals (frequency > 1% of population) Genetic variation

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360 views • 34 slides



Data Mining in Linkage Disequilibrium Mapping

Data Mining in Linkage Disequilibrium Mapping

Data Mining in Linkage Disequilibrium Mapping. Jing Hua Zhao Epidemiology j.zhao@public-health.ucl.ac.uk June 2003. Outline of the Talk. The problem Why data mining? Haplotype construction Challenging issues. Current Paradigm. Complex traits (Lander & Schork 1994)

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303 views • 15 slides


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