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Medical Natural Sciences Year 2: Introduction to Bioinformatics

Medical Natural Sciences Year 2: Introduction to Bioinformatics. Lecture 8: Multiple sequence alignment (II) Centre for Integrative Bioinformatics VU. Progressive multiple sequence alignment. Accuracy is very important Problem: Errors are propagated through the progressive steps

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Multiple sequence alignment Why?

Multiple sequence alignment Why?. It is the most important means to assess relatedness of a set of sequences Gain information about the structure/function of a query sequence (conservation patterns) Construct a phylogenetic tree Putting together a set of sequenced fragments (Fragment assembly)

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Medical Natural Sciences Year 2: Introduction to Bioinformatics

Multiple sequence alignment Why?