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Hydroxylation - PowerPoint PPT Presentation


Chapter 3 Chemical Structure and Metabolism

Chapter 3 Chemical Structure and Metabolism

Chapter 3 Chemical Structure and Metabolism. 第三章  化学结构与药物代谢. Section 1 Introduction. The physicochemical properties of drugs that predispose ( 使偏向于 ) them to good absorption, such as lipophilicity ( 亲脂性 ) , are impediment( 妨碍 ) to their elimination.

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2.25k views • 183 slides



Metabolism of Xenobiotics

Metabolism of Xenobiotics

ENVR/TOXC 442 Fall 2012. Metabolism of Xenobiotics. II. Phase 1 Metabolism Aug 23, 2012 L.M. Ball Rosenau 158 lmball@unc.edu. Phase I reactions. Chemical modification of xenobiotics Introduces or uncovers polar functional groups that provide sites for Phase II metabolism

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525 views • 39 slides


Metabolism of Xenobiotics

Metabolism of Xenobiotics

ENVR/TOXC 442 Fall 2012. Metabolism of Xenobiotics. II. Phase 1 Metabolism Aug 23, 2012 L.M. Ball Rosenau 158 lmball@unc.edu. Phase I reactions. Chemical modification of xenobiotics Introduces or uncovers polar functional groups that provide sites for Phase II metabolism

★ ★ ★ ★ ★

488 views • 39 slides


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