'Ig gene rearrangement' diaporamas de présentation

The development of lymphocytes

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Ch4. Antibody Structure and the Generation of B-cell diversity

Ch4. Antibody Structure and the Generation of B-cell diversity. B-Cell Receptor (BCR). Immunoglobulin(Ig), antibody specificity: one antibody for one antigen or a few different antigens diversity: as high as 10 16 of antibody repertoire; in practice about 10 9

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Organization and Expression of Immunoglobulin Genes

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Organization and Expression of Immunoglobulin Genes

Organization and Expression of Immunoglobulin Genes. Reading. Chapter 5 Kuby et al Immunology 6 th Edition. OBJECTIVES. Define the following terms: allelic exclusion, isotype switching, affinity maturation , antibody repertoire, alternative RNA splicing, recombination signal sequence

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