Insulin Bioreactor Design. CHEE 450 Thursday, March 29. Reactor Considerations. Production of insulin precursor 5000 kg insulin per year Assumes 20 % loss due to purification k L a within 10% of 2088 hr -1 Prevents oxygen limited reaction Prevents anaerobic metabolismBy fedella
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Insulin Bioreactor Design. CHEE 450 Thursday, March 29. Reactor Considerations. Production of insulin precursor 5000 kg insulin per year Assumes 20 % loss due to purification k L a within 10% of 2088 hr -1 Prevents oxygen limited reaction Prevents anaerobic metabolism
Chapter 3: Bioreactor Design. Product Requirement. Biological System Identification. Stoichiometry and Medium Design. Heat & Mass Transfer Constraints. Upstream Constraints. Kinetics. Plasmid stability. Shear sensitivity. Bioreactor Type Selection. Downstream Constraints.
Insulin Production Design Project. Fermentor Optimization. Group Members: Shaina Dinsdale Mike Hull Dean Latham Chris Tovee. Source: http://www.ingenious.org.uk. Outline. Fermentors in general Alternatives- Batch vs CSTR Our Design Design method Cost and Suppliers Questions.
Tissue Bioreactor. by Rachel Mosher, Joel Gaston, Kara Barnhart Client: Susan Thibeault Advisor: Brenda Ogle (October 19, 2007). Outline. Stimulating Vocal Fold Environment Vocal Folds Bioreactor Background Vibratory and Operational Requirements Rotation Problem Solution Ideas
BIOREACTOR CONFIGURATIONS. Usually, a cylindrical tank, either stirred or unstirred. Reactor design Provision of adequate mixing and aeration for the large proportion of fermentations requiring oxygen. Stirred Tank Reactors (STRs).
BIOREACTION AND BIOREACTOR. By: Mdm. Noor Amirah Abdul Halim. WHAT IS BIOREACTOR?. A special reactor that sustains and supports life for cells and tissue cultures. Used in industrial processes to produce pharmaceuticals, vaccines, or antibodies
The bioreactor. Part Ⅱ Chapter 2. For each biotechnology process the most suitable containment system must be designed to give the correct environment for optimising the growth and metabolic activity of the biocatalyst.
Bioreactor/Fermentor Schematic. Critical Concerns of Bioreactor and Fermentation Applications. Oxygenation Requirements Shear (In fluid transfer and foam) Flow Requirements Filtration/Heat sterilization concerns Transportation of Bulk Product Containment of Biohazard and other waste.
Phototrophic Bioreactor – Fermentor. Temperature controlled. Temperature sensor pt1000 Fast reaction time Temperature profiles. Cooling and heating system. From 5 to 70 (120) Celsius 2 Peltiers elements Fast reaction and temperature profiles No water cooling. Built in – DM Fluorometr.
ERT314 BIOREACTOR SYSTEM. CHAPTER 2: BIOLOGICAL SYSTEMS AND MEDIA DESIGN. 2.1 Introduction to Biological System. ** rheology – the study of the flow of matters, especially in liquid state. Fermentation with fungi. Fermentation with bacteria. Oxygen Demand. OTR = Oxygen transfer rate