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Integrin - PowerPoint PPT Presentation


CONTACT INFORMATION: LUISA IRUELA-ARISPE MBI/BOYER HALL 559 PHONE# 310 - 794-5763

CONTACT INFORMATION: LUISA IRUELA-ARISPE MBI/BOYER HALL 559 PHONE# 310 - 794-5763

CELL-MATRIX INTERACTIONS Lecture 3 January 13th, 2006. CONTACT INFORMATION: LUISA IRUELA-ARISPE MBI/BOYER HALL 559 PHONE# 310 - 794-5763 arispe@mbi.ucla.edu. Extracellular matrix. integrin. Src. cytosol. Grb2. Sos. Raf. MAP kinase cascade. Actin filament. actinin. nucleus.

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351 views • 22 slides



1978

1978

Fibronectin shown to colocalize with fibrillar actin. Proposed a transmembrane relationship between microfilaments and FN . Phosphotyrosine is detected in focal adhesions. Receptors for matrix proteins purified. Addition of fibronectin to tumor cells induces cell flattening and

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242 views • 3 slides


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