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Ire1 initiates - PowerPoint PPT Presentation

Major Claims

Major Claims. IRE1 initiates an XBP-1 independent pathway during the unfolding protein response IRE1 nuclease has a broader range of substrates than XBP-1 IRE1 mediates the rapid degradation of a subset of mRNA Degradation is dependent on ER localization and peptide sequence. No treatment.

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Ire1 initiates - PowerPoint PPT Presentation

Major Claims