'Kit mutations' diaporamas de présentation

GIST Overview

GIST Overview. GIST: Definition. Mesenchymal (connective tissue) neoplasms Located primarily in the GI tract, omentum, and mesentery 0.2% of all GI tumors 80% of GI sarcomas Usually stain positive for KIT. GI, gastrointestinal; HU, Hounsfield units.

788 views • 57 slides

Annual GIST Breakfast

Annual GIST Breakfast. Heinrich & Corless Laboratories Knight Cancer Institute Oregon Health & Science University. Topics. An review of projects and the people working on them Corless group: Wild-type GIST project Heinrich group: Drug screening team Combination therapy

607 views • 35 slides

c-kit

580 views • 18 slides

c-Kit

c-Kit. Piebaldism Gastrointestinal stromal tumors. c-Kit. A proto-oncogene Encodes a receptor tyrosine kinase type III (similar to PDGFR). Family characteristics: 5 immunoglobulin-like (Ig) domains Cytoplasmic tyrosine kinase domain with large kinase insert.

473 views • 16 slides