'Linked dominant' diaporamas de présentation

MENDELIAN INHERITANCE

MENDELIAN INHERITANCE. Mohammed El - Khateeb June 30 th . 2014 MGL- 6. Homozygous Dominant + Heterozygous. Homozygous Dominant + Homozygous Dominant. Homozygou dominant Homozygou dominant. Hetrozygous Recessive + Heterozygous Recessive. Hetrozygous dominanat + Hetrozygous Recessive.

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MENDELIAN INHERITANCE

MENDELIAN INHERITANCE. Mohammed El - Khateeb June 30 th . 2014 MGL- 6. Genetic Diseases (GD). Chromosomal Abnormalities Single Gene Defects Non-Traditional Inheritance Multifactorial Disorders Cancer Genetics. Topics of Discussion. Basic concepts of formal genetics

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Concept 4

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Concept 4

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Human Genetics

Human Genetics. NonAutosomal Inheritance. NonAutosomal Inheritance. X-Linked Dominant X-linked Recessive Y-linked Mitochondial. The Sex Chromosomes. The Sex Chromosomes. There is no universal system; can be either genetic or environmental Humans and fruit flies have the XY genetic system

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Human Genetics

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Pedigree

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Genes in Pedigrees & Populations Monogenic versus multifactorial inheritance:

Genes in Pedigrees & Populations Monogenic versus multifactorial inheritance: Over 6000 Mendelian characters are known in humans (OMIM databse www.ncbi.nlm.nih.gov/Omim/ Multifactorial trait may involve a small number of loci (oligogenic) or many loci (polygenic)

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Explain this pedigree

Please Take Out The Following: Pencil Science Journal: Notes Portion Chapter 8 Homework Packet *If you have not taken the Chapter 8 Quiz from yesterday, SEE ME NOW !. Explain this pedigree. In sex-linked traits only females can be carriers.

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Sex linkage and Pedigrees

Sex linkage and Pedigrees. Sex determination in mammals. In humans and some other organisms, X and Y chromosomes determine the sex of an individual.

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Sex linkage and Pedigrees

Sex linkage and Pedigrees. Sex determination in mammals. In humans and some other organisms, X and Y chromosomes determine the sex of an individual.

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Vikki Moye, November 2007

Outline the patterns of inheritance associated with X-linked genes. Where possible give a molecular explanation for the pattern. Vikki Moye, November 2007. X-linked inheritance. When a gene for particular disease/trait lies on the X chromosome it is X-linked

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THE STEPS WHEN INTERPRETING A PEDIGREE CHART

THE STEPS WHEN INTERPRETING A PEDIGREE CHART. Determine if the pedigree chart shows an autosomal or X-linkeddisease. If most of the males in the pedigree are affected, then the disorder is X-linked If it is a 50/50 ratio between men and women the disorder is autosomal.

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Sex Linked Genes

Sex Linked Genes. Sex Linked Genes. Found on 23rd chromosome. If a gene is found only on the X chromosome and not the Y chromosome, it is said to be a sex-linked trait . Sex linkage is linked to the gender of the individual. X Chromosome. Y Chromosome. X R. X R. X R.

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Sex Linked Inheritance

Sex Linked Inheritance. A human female, has 23 pair of chromosomes A human male, has 22 similar pairs and one pair consisting of two chromosomes that are dissimilar in size and structure. The 23 rd pair in both the sexes is called sex chromosomes the female, XX. the male, XY.

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Heredity Teachable Unit: Mendelian Inheritance

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Pedigree Notes

Pedigree Notes. What are pedigrees?. Pedigrees track traits within lines of descent (family trees) and are used to figure out the method of inheritance of certain traits (usually diseases). Methods of inheritance. Autosomal dominant: dominant trait carried on chromosomes in pairs 1-22

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MAKING PUNNETT PREDICTIONS

MAKING PUNNETT PREDICTIONS. http://www.exploratorium.edu/exhibits/mutant_flies/mutant_flies.html. IF GENE is AUTOSOMAL and RECESSIVE TO + MALES:FEMALES 1:1. F 1 ___________________. F 2 ___ = ___ ______________ ___ = ___ ___ = ___ ______________

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MAKING PUNNETT PREDICTIONS

MAKING PUNNETT PREDICTIONS. http://www.exploratorium.edu/exhibits/mutant_flies/mutant_flies.html. IF GENE is AUTOSOMAL and RECESSIVE TO + MALES:FEMALES 1:1. F 1 ___________________. F 2 ___ = ___ ______________ ___ = ___ ___ = ___ ______________

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Pedigrees

Pedigrees. First Decision. Is it autosomal or X-linked inheritance?. Autosomal: both genders are equally affected; male-to-male transmission observed If not, propose X-linkage. Second Decision. Is it dominant or recessive?.

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